Protein Alignment CCKLR-17D3 and galr2

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_002940025.1
• Gene: galr2 / 100486593
• XenbaseID: XB-GENE-921716
• Length: 373
• Species: Xenopus tropicalis
• Alignment Length: 464
• Identity: 103/464 - (22%)
• Similarity: 173/464 - (37%)
• Gaps: 139/464 - (29%)

  Fly   114 LIP-SYSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNF 177
            ||| .||:|.|...:||.||::.|::|.::...||:|:|||.::|:...:.|:|.......|.::
 Frog    19 LIPVLYSLIFLVGTVGNSLVLAVLLRNGKVNNTTNLFILNLGVADLCFIIFCVPFQATIYTLDSW 83

  Fly   178 IFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILC 242
            :||.|:||...|....::..||:||..:|.:||.||.:|||||..:|..:|...|..||...::.
 Frog    84 VFGPFMCKAVHFFIYLTMYASSFTLTTVSLDRYLAIRYPLRSRELRTPKNALLAITLIWSLSLVF 148

  Fly   243 MTPIAVFSQLIPTSRPGYCKCREFWPDQGYELFYNILLDFLLL----VLPLLVLCVAYILITRTL 303
            ..|...:.|....|  ....|...|.|.     |...:|....    |:|:|:|.:.|....|.|
 Frog   149 SGPYLSYYQEFQLS--NLTVCHPVWQDS-----YRRAMDLCTFAFSYVIPVLILSLTYARTIRYL 206

  Fly   304 YVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGG 368
            :                        :|.:|
 Frog   207 W------------------------TAVDP----------------------------------- 212

  Fly   369 GSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLF 433
                                                        :...:|:|  .:|:||.:|:.
 Frog   213 --------------------------------------------IEDMSESK--RAKRRVTRMII 231

  Fly   434 VLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFLQLLAYSSSCCNPITYCFMNASFRRAF 498
            ::.:.|.:||.|.::: .:.:..|........|.......|::|::||.||:.|..::..||:.|
 Frog   232 IVAVLFCLCWLPHHLV-ILCVWFGYFPLNNFTYALRILSHLVSYANSCVNPVVYALVSKHFRKGF 295

  Fly   499 VDTFKGLPWRRGAGASGGVGGAAGGGLSASQAGAGPGAYASANTNIS----------LNPGLAMG 553
            ...|:.|..|:.|........|...|:|..:   ||   .:..|:||          .:||
 Frog   296 RKIFRCLLLRQRAANKVHTAPATHVGVSTHE---GP---CTEVTHISEGHLHCSACCPDPG---- 350

  Fly   554 MGTWRSRSR 562
             ..|:...|
 Frog   351 -SPWKETER 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	86/388 (22%)
		TM helix 1	114..138	CDD:320334	12/24 (50%)
		TM helix 2	147..169	CDD:320334	8/21 (38%)
		TM helix 3	185..207	CDD:320334	6/21 (29%)
		TM helix 4	230..246	CDD:320334	3/15 (20%)
		TM helix 5	274..297	CDD:320334	6/26 (23%)
		TM helix 6	429..451	CDD:320334	5/21 (24%)
		TM helix 7	466..491	CDD:320334	8/24 (33%)
galr2	XP_002940025.1	7tmA_Gal2_Gal3_R	18..295	CDD:320225	86/388 (22%)
		TM helix 1	19..45	CDD:320225	12/25 (48%)
		TM helix 2	52..78	CDD:320225	9/25 (36%)
		TM helix 3	90..120	CDD:320225	11/29 (38%)
		TM helix 4	132..152	CDD:320225	4/19 (21%)
		TM helix 5	176..205	CDD:320225	6/28 (21%)
		TM helix 6	221..251	CDD:320225	8/30 (27%)
		TM helix 7	263..288	CDD:320225	8/24 (33%)