Protein Alignment CCKLR-17D3 and qrfpra

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_021336543.1
• Gene: qrfpra / 100149491
• ZFINID: ZDB-GENE-090313-105
• Length: 422
• Species: Danio rerio
• Alignment Length: 451
• Identity: 97/451 - (21%)
• Similarity: 171/451 - (37%)
• Gaps: 144/451 - (31%)

  Fly    69 RDGYMDT---EPSDLVTELAFSLGTSSSPSPSSTPASSSSTSTGMPVWLIPSYSMILLFAVLGNL 130
            |..:::|   ||...:.||               ||.:.:|       .:..|::|.|.|::||.
Zfish    22 RQEFIETYQIEPLVYIPEL---------------PAGAKTT-------FVIVYTVIFLLALVGNS 64

  Fly   131 LVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEFLCKLFQFSQAASV 195
            :|:..:::.|.::|.||:|:.:||:||:|:...|:|.||:..:...:..|..:||...|.|..:|
Zfish    65 VVVYIVLRKRGIQTATNIFICSLAVSDLLISFFCIPFTLLQNISSEWFGGVLVCKTVPFVQTTAV 129

  Fly   196 AVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIAVFSQL-----IPT 255
            .....|:..|:.|||..|.|||:.:...|...||:::|.:|:..::..:|:....||     ...
Zfish   130 VTGILTMTCIAVERYQGIVHPLKIKRQCTPQRAYRMLGVVWIAAMMVGSPMLFVQQLEVKYDFLY 194

  Fly   256 SRPGYCKCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAKDSGRILQQSLP 320
            .....| |:|.|....:...|...:...|.:|||..:.:.|..|...|::
Zfish   195 DNHHVC-CQERWRSSAHRKRYATFILVFLFLLPLAAMLILYTRIGIELWI--------------- 243

  Fly   321 VSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAP 385
                     ....|.||..|
Zfish   244 ---------RKQVGDSSVLN--------------------------------------------- 254

  Fly   386 TVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVIN 450
                                      |:.:...:|....|:|.:||:..:|:.|.:||.|.:.::
Zfish   255 --------------------------AMNQREVSKIARKKRRAIKMMVTIVVLFTVCWAPFHTVH 293

  Fly   451 TMVMLIGPVVYEYV-------DYTA---ISFLQLLAYSSSCCNPITYCFMNASFRRAFVDT 501
                    :::||.       |.|.   |:..|.:.:|:|..|||.|.|||.:|::..:.|
Zfish   294 --------ILFEYSYLNKKYDDVTVNMIIAVAQAIGFSNSFNNPIIYAFMNENFQKNCMST 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	87/400 (22%)
		TM helix 1	114..138	CDD:320334	7/23 (30%)
		TM helix 2	147..169	CDD:320334	9/21 (43%)
		TM helix 3	185..207	CDD:320334	6/21 (29%)
		TM helix 4	230..246	CDD:320334	2/15 (13%)
		TM helix 5	274..297	CDD:320334	5/22 (23%)
		TM helix 6	429..451	CDD:320334	7/21 (33%)
		TM helix 7	466..491	CDD:320334	10/27 (37%)
qrfpra	XP_021336543.1	7tmA_QRFPR	46..343	CDD:320333	88/407 (22%)
		TM helix 1	47..73	CDD:320333	8/32 (25%)
		TM helix 2	80..106	CDD:320333	12/25 (48%)
		TM helix 3	118..148	CDD:320333	10/29 (34%)
		TM helix 4	161..182	CDD:320333	5/20 (25%)
		TM helix 5	211..236	CDD:320333	6/24 (25%)
		TM helix 6	266..296	CDD:320333	9/37 (24%)
		TM helix 7	311..336	CDD:320333	9/24 (38%)