Protein Alignment CCKLR-17D3 and cckbra

DIOPT Version :10

• Sequence 1: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001108186.2
• Gene: cckbra / 100137117
• ZFINID: ZDB-GENE-060503-482
• Length: 444
• Species: Danio rerio
• Alignment Length: 394
• Identity: 151/394 - (38%)
• Similarity: 215/394 - (54%)
• Gaps: 63/394 - (15%)

  Fly   118 YSMILLFAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIFGEF 182
            ||::.|.:|.||||:|..|:.|:||||:||.|||:||:||:::.:.|:|..|:.:||.:||||..
Zfish    63 YSLVFLLSVFGNLLIIVVLIVNKRMRTVTNSFLLSLAVSDLMMAIFCIPFNLIPSLLEDFIFGAA 127

  Fly   183 LCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIA 247
            :||...:....||::|:::||||:.|||.|||:||:||:|||.|||||:|...|:..:..|.|..
Zfish   128 MCKTVAYFMGISVSISTFSLVAIAIERYSAICNPLKSRAWQTRSHAYKVIAATWVLSVAIMVPYP 192

  Fly   248 VFSQLIPTSRPGYC---KCREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAK 309
            |||.|:|.::....   .||..||....|..:.:||..:|..:|.:|:.:||.||:|.||.|:..
Zfish   193 VFSILVPFNKTNNITAHMCRLEWPISQVEQTWYVLLLSILFFIPGVVMIIAYGLISRELYRGIQF 257

  Fly   310 DSGRILQQSLPVSATTAGGSAPNPGTSS----SSNCILVLTATAVYNENSNNNNGNSEGSAGGGS 370
            :    |:|....|....|   .|.|.||    |..|.:
Zfish   258 E----LEQKKDTSGVKNG---LNGGLSSCHDESDGCYI--------------------------- 288

  Fly   371 TNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSN--EAKTLESKKRVVKMLF 433
                  .::.:|.|..:.|.||:..|   ||..|          |||  ||| |.:||||::||.
Zfish   289 ------QVSKKPPAMELSTLTTSGPV---KTDRP----------RSNTSEAK-LIAKKRVIRMLI 333

  Fly   434 VLVLEFFICWTPLYVINTMVMLIGPVVYEYVDYTAISFLQLLAYSSSCCNPITYCFMNASFRRAF 498
            ::|..||:||.|||..||............:....|||:|||:|:|:|.|||.|||||..||:|.
Zfish   334 IIVAMFFVCWMPLYSANTWKAFDQISAQRALSGAPISFIQLLSYTSACVNPIIYCFMNTRFRKAL 398

  Fly   499 VDTF 502
            :.||
Zfish   399 LATF 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D3	NP_001097023.1	7tm_GPCRs	112..498	CDD:475119	148/388 (38%)
		TM helix 1	114..138	CDD:320334	10/19 (53%)
		TM helix 2	147..169	CDD:320334	10/21 (48%)
		TM helix 3	185..207	CDD:320334	8/21 (38%)
		TM helix 4	230..246	CDD:320334	4/15 (27%)
		TM helix 5	274..297	CDD:320334	6/22 (27%)
		TM helix 6	429..451	CDD:320334	10/21 (48%)
		TM helix 7	466..491	CDD:320334	15/24 (63%)
cckbra	NP_001108186.2	7tmA_CCK-BR	57..398	CDD:320645	148/388 (38%)
		TM helix 1	58..84	CDD:320645	10/20 (50%)
		TM helix 2	91..117	CDD:320645	12/25 (48%)
		TM helix 3	129..159	CDD:320645	13/29 (45%)
		TM helix 4	172..193	CDD:320645	8/20 (40%)
		TM helix 5	221..250	CDD:320645	10/28 (36%)
		TM helix 6	323..353	CDD:320645	16/29 (55%)
		TM helix 7	366..391	CDD:320645	15/24 (63%)