Protein Alignment CCKLR-17D1 and npy1r

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001095861.1
• Gene: npy1r / 793668
• ZFINID: ZDB-GENE-080221-1
• Length: 380
• Species: Danio rerio
• Alignment Length: 541
• Identity: 120/541 - (22%)
• Similarity: 195/541 - (36%)
• Gaps: 193/541 - (35%)

  Fly   138 LNLDMDLATTPSSSTLAPAVTVRTPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLTLVQ 202
            ||..:||:....::..|.|......|:.|:..:.|       ..|||::|..|:|||.::|.:.:
Zfish    16 LNCSLDLSNCSITNLSAIAYGDECYGSHSLFVIMA-------VAYSAVVLLGVIGNLALILVIAR 73

  Fly   203 NRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVSSWTLV 267
            .|.:..:|||.:.||::||:|:.|.|:|.|.:.|.:.|::||.::|||....|..||:||.::||
Zfish    74 QRELHNVTNVLIANLSVSDLLMAVVCLPFTFIYTFMDHWVFGAVMCKLNSLVQCCSVSVSIFSLV 138

  Fly   268 AISCERYYAICHPLRSRTWQ-TINHANKIIAIIWLGSLVCMTPIAAFSQLMPTSRP--------- 322
            .|:.||:..|.||   |.|: ::|||...|::.|..:::..||...||::  |..|
Zfish   139 LIAIERHQLILHP---RGWRPSLNHACLGISLTWALAVLTATPFLLFSRV--TDAPLKQLPSVFQ 198

  Fly   323 ----GLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFGS 383
                |...|.|:||:      |...|.....:|||..:. ..|::||
Zfish   199 EQYRGKVVCVEEWPS------REIKLTYTTGMLVLQYIT-PLTFIFI------------------ 238

  Fly   384 SGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLIS 448
                                                                             
Zfish   239 ----------------------------------------------------------------- 238

  Fly   449 GGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSD 513
                                                       |..:::...|
Zfish   239 -------------------------------------------CYLKIYTRLQ------------ 248

  Fly   514 NESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGP 578
               ||.::.:   ||      |.|:.:|.|| ||:..|||.:|:.|.:||.||.|.|.:......
Zfish   249 ---RRNNMME---RI------RENKYRSSES-KRINIMLFSIVVAFAVCWLPLNVFNAVIDWNHE 300

  Fly   579 TVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLCAPCCFWRRRSK 643
            ...........|...|.|..|.|.||:.|.|:|.:|:|    ..:..|:|:.:..     |....
Zfish   301 VAMNCTHNLLFSLCHLTAMCSVCINPVFYGFLNRNFQR----DLRAFRLCKIVST-----RENEY 356

  Fly   644 NETNLSVAGNSIALANSVMSS 664
            :...:|.....::..:..|||
Zfish   357 DMVAMSTVNTDVSKMSLKMSS 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	104/454 (23%)
		TM helix 1	178..202	CDD:410628	9/23 (39%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	10/21 (48%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	6/22 (27%)
		TM helix 6	549..571	CDD:410628	10/21 (48%)
		TM helix 7	586..611	CDD:410628	9/24 (38%)
npy1r	NP_001095861.1	7tmA_NPY1R	47..340	CDD:320517	105/466 (23%)
		TM helix 1	48..74	CDD:320517	10/32 (31%)
		TM helix 2	81..106	CDD:320517	12/24 (50%)
		TM helix 3	119..149	CDD:320517	13/29 (45%)
		TM helix 4	160..181	CDD:320517	6/20 (30%)
		TM helix 5	217..246	CDD:320517	8/155 (5%)
		TM helix 6	265..295	CDD:320517	15/30 (50%)
		TM helix 7	308..333	CDD:320517	9/24 (38%)