Protein Alignment CCKLR-17D1 and qrfpr

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_012820557.1
• Gene: qrfpr / 779748
• XenbaseID: XB-GENE-994316
• Length: 456
• Species: Xenopus tropicalis
• Alignment Length: 497
• Identity: 105/497 - (21%)
• Similarity: 177/497 - (35%)
• Gaps: 192/497 - (38%)

  Fly   185 ILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCK 249
            |.:.|:.||.||:..:.:::.|||:||:|:.:||:||:|:..||:|.|::..:..:::.|...||
 Frog    89 IFVLALFGNSLVLYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPFTMLQNISSNWLGGAFACK 153

  Fly   250 LIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTIN-HANKIIAIIWLGSLVCMTPIAAF 313
            ::.|.|:.::.....|:..|:.||:..|.|||:.: ||..| .|..::.|:||.:.|...|: ..
 Frog   154 MVPFVQSTAIVTEILTMTCIAVERHQGIVHPLKMK-WQYTNRRAFTMLGIVWLIAAVVGIPM-WH 216

  Fly   314 SQLMPTSRPGLRK-----CREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSM 373
            :|.:......|.:     |.|.|  :|..:::.|..|:.:.|.:|||..:...|..|...|::..
 Frog   217 AQRLEVKYDFLYEKQYVCCLEAW--NSQVHQKIYTTFILVILFLLPLTVMLLLYSKIGYELWIKK 279

  Fly   374 RNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYG 438
            |
 Frog   280 R---------------------------------------------------------------- 280

  Fly   439 HCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQM 503
                                   :..|||.    |.|:|
 Frog   281 -----------------------VGDASVL----QTIHG-------------------------- 292

  Fly   504 QLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYV 568
                                            |..:|....|||.:.|:..:|:.|.:||.|.:|
 Frog   293 --------------------------------SEMSKIARKKKRAIIMMITVVVLFAVCWAPFHV 325

  Fly   569 INTMTMLLGPTVYEYVGYTS----------ISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFK 623
            ::.|        .||..:.:          .:.:|::.:.:|.||||.|.|||.:|::.|:..
 Frog   326 VHMM--------IEYSNFENEYDDVTIKIIFAIVQIIGFFNSICNPIVYAFMNENFKKNFLSA-- 380

  Fly   624 GMRVCERLCAPCCFWRRRSKNETNLSVAGNS-IALANSVMSS 664
                   ||  .||.|..|.....   .||| |.|.....||
 Frog   381 -------LC--FCFLRDPSSPSRR---PGNSGITLIQQKSSS 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	91/448 (20%)
		TM helix 1	178..202	CDD:410628	6/16 (38%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	5/21 (24%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	6/22 (27%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	8/34 (24%)
qrfpr	XP_012820557.1	7tmA_QRFPR	80..377	CDD:320333	91/448 (20%)
		TM helix 1	81..107	CDD:320333	6/17 (35%)
		TM helix 2	114..140	CDD:320333	12/25 (48%)
		TM helix 3	152..182	CDD:320333	8/29 (28%)
		TM helix 4	195..216	CDD:320333	6/21 (29%)
		TM helix 5	245..270	CDD:320333	7/24 (29%)
		TM helix 6	300..330	CDD:320333	11/37 (30%)
		TM helix 7	345..370	CDD:320333	8/24 (33%)