Protein Alignment CCKLR-17D1 and sstr1a

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_073784295.1
• Gene: sstr1a / 568254
• ZFINID: ZDB-GENE-090429-1
• Length: 366
• Species: Danio rerio
• Alignment Length: 489
• Identity: 94/489 - (19%)
• Similarity: 171/489 - (34%)
• Gaps: 191/489 - (39%)

  Fly   176 IWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRH 240
            |::...||.:.|..:.||.:|:..:.:..:|:|.||:::|||||:|.|| :..:|..:..:||.|
Zfish    34 IFISFIYSVVCLVGLCGNSMVIYVIFRYAKMKTATNIYILNLAIADELL-MLSVPFLVTSSLLHH 97

  Fly   241 FIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLV 305
            :.||.|||:|:....|.::..|.:.|..:|.:||.::.||:::..::....|..:...:|:.|::
Zfish    98 WPFGSLLCRLVLSVDAINMFTSIYCLTVLSIDRYISVVHPIKAARYRRPTIAKMVNLAVWMFSIL 162

  Fly   306 CMTPIAAFSQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLY 370
            .:.||..||...|.| .|...|..|.|.....:...:.::..|...:.|::|:...|:.|    .
Zfish   163 VILPIIIFSTTAPNS-DGSVACNMQMPEPERQWMAVFVIYAFLMGFLFPVIAICMCYILI----I 222

  Fly   371 VSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYY 435
            |.||                   ....:||.|:|.
Zfish   223 VKMR-------------------VVALKAGWQQRK------------------------------ 238

  Fly   436 DYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMR 500
                                                                             
Zfish   239 ----------------------------------------------------------------- 238

  Fly   501 QQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTP 565
                                                      :|::::..|:.::|..|.|||.|
Zfish   239 ------------------------------------------KSERKITLMVMMVVTVFVICWMP 261

  Fly   566 LYVINTMTMLLGPTVYEYVGYTSISFLQL---LAYSSSCCNPITYCFMNASFRRAFVDTFKGMRV 627
            .:::..:::        :|...:.:..||   |.|::||.|||.|.|::.:|||:|
Zfish   262 FHIVQLVSV--------FVQQHNATLSQLAVILGYANSCANPILYGFLSDNFRRSF--------- 309

  Fly   628 CERLCAPCCFWRRRSKNE------TNLSVAGNSI 655
             :|:.  |..|...:..|      |.|...|.|:
Zfish   310 -QRIL--CLRWWENATEEPIDYYATALKSRGYSV 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	84/443 (19%)
		TM helix 1	178..202	CDD:410628	6/23 (26%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	4/21 (19%)
		TM helix 4	294..310	CDD:410628	2/15 (13%)
		TM helix 5	340..363	CDD:410628	3/22 (14%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	11/27 (41%)
sstr1a	XP_073784295.1	None