Protein Alignment CCKLR-17D1 and tacr1b

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001268728.1
• Gene: tacr1b / 564017
• ZFINID: ZDB-GENE-091117-17
• Length: 412
• Species: Danio rerio
• Alignment Length: 503
• Identity: 108/503 - (21%)
• Similarity: 174/503 - (34%)
• Gaps: 190/503 - (37%)

  Fly   146 TTPSS-----STLAPAVTVRTPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLTLVQNRR 205
            |:|:|     |..:|.......||:.|..| ..:.:|.: .|..|:|.:||||:.|:..::.::|
Zfish     7 TSPNSSADNGSAGSPVNDTEVFGNQFVQPV-WQIVLWAI-AYCTIVLVSVVGNITVIWIILAHKR 69

  Fly   206 MRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVSSWTLVAIS 270
            |||:||.||:|||.::..:..|...:..:..:...:.||.:.|:...|...|:|..|.:::.||:
Zfish    70 MRTVTNYFLVNLAFAEASMSAFNTVINFIYAVHNEWYFGLVYCRFHNFFPIAAVFASIYSMTAIA 134

  Fly   271 CERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFSQLMPTSRPGLRKCREQWPADS 335
            .:||.||.|||:.|.  :......::.:||..:|:...|...||.  ....||...|...||..|
Zfish   135 LDRYMAIIHPLQQRL--SSAETKLVVCVIWALALMLAFPQYYFSS--TAQLPGRVVCYINWPEYS 195

  Fly   336 L-NYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEA 399
            : ::::.|.:.:.:.:..||||.:...||.:...|:.|              |:...||
Zfish   196 MWDFQKTYYVCVVVLIYFLPLLVMGCAYLVVGCFLWAS--------------EIPGDSS------ 240

  Fly   400 GSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRS 464
                                                                             
Zfish   241 ----------------------------------------------------------------- 240

  Fly   465 ASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRIT 529
                                            .|.|:|
Zfish   241 --------------------------------DRYREQ--------------------------- 246

  Fly   530 EAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVYE-------YVGYT 587
                        |.:|::||||:.|:|..|..||.|.:|...:...| |.::|       |:|
Zfish   247 ------------LIAKRKVVKMMIVVVCTFATCWLPYHVYFIVHQFL-PHLFEERYIQQVYLG-- 296

  Fly   588 SISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLCAPC 635
                :..||.||:..|||.||.:|..||..|...|.        ..||
Zfish   297 ----IMWLAMSSTMYNPIIYCLLNDRFRAGFQQAFS--------WCPC 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	95/448 (21%)
		TM helix 1	178..202	CDD:410628	8/23 (35%)
		TM helix 2	211..233	CDD:410628	7/21 (33%)
		TM helix 3	249..271	CDD:410628	6/21 (29%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	10/21 (48%)
		TM helix 7	586..611	CDD:410628	9/24 (38%)
tacr1b	NP_001268728.1	7tm_GPCRs	40..323	CDD:475119	95/450 (21%)
		TM helix 1	42..66	CDD:410628	9/24 (38%)
		TM helix 2	75..97	CDD:410628	7/21 (33%)
		TM helix 3	113..135	CDD:410628	6/21 (29%)
		TM helix 4	156..172	CDD:410628	3/15 (20%)
		TM helix 5	201..224	CDD:410628	5/22 (23%)
		TM helix 6	254..276	CDD:410628	10/21 (48%)
		TM helix 7	291..316	CDD:410628	11/30 (37%)