Protein Alignment CCKLR-17D1 and galr1b

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001314772.1
• Gene: galr1b / 561989
• ZFINID: ZDB-GENE-140624-1
• Length: 350
• Species: Danio rerio
• Alignment Length: 500
• Identity: 103/500 - (20%)
• Similarity: 167/500 - (33%)
• Gaps: 199/500 - (39%)

  Fly   142 MDLATTPSSSTLAPAVTVRTPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLTL--VQNR 204
            ||  |..::.|..|.|.:              ||:    .:..|....::||.||::.:  :::|
Zfish    20 MD--TNQTTDTFGPEVVI--------------VPV----IFGCIFFLGIIGNTLVMVVIGKIKSR 64

  Fly   205 RMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVSSWTLVAI 269
            |.|:.||:|:|||:|:|:...:||:|.......|..:|||..|||.:.:....|:.||.:||||:
Zfish    65 RSRSTTNIFILNLSIADLSFLLFCVPFQATIYSLPEWIFGAFLCKFVHYFVMVSMLVSIFTLVAM 129

  Fly   270 SCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFSQLMPTSR-PGLRKCREQWPA 333
            |.:||.|:....:|...:...:|...:.:||:.|.:...|:|....|....: |....|.|.|.
Zfish   130 SVDRYIAVVLSKKSPCIRNRRNALIGVCVIWMLSFIFAVPVAQHQILTDHPKAPNSTFCWEIWT- 193

  Fly   334 DSLNYERAYNLFLDLALLV----LPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSA 394
                 ||.......:.:||    ||||.::..|   .:.||
Zfish   194 -----ERVAKHTYKVTILVIGYLLPLLLITCCY---AKVLY------------------------ 226

  Fly   395 AVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHL 459
                                                                           ||
Zfish   227 ---------------------------------------------------------------HL 228

  Fly   460 YCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQP 524
                        |::|                                           |::|:
Zfish   229 ------------HKKI-------------------------------------------KNMSK- 237

  Fly   525 SLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVYEYVGYTSI 589
                           ||..||::..:.:.::|..|.|||.|.::| .|.:..|........:...
Zfish   238 ---------------KSERSKRKTAQTVLLVVAAFLICWMPHHII-AMWVEFGQFPLNDASFAFR 286

  Fly   590 SFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLCAP 634
            .....|||.:||.|||.|.|::.:||:|....|    .|....:|
Zfish   287 IISHCLAYGNSCVNPILYAFLSENFRKACKQVF----TCRFFYSP 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	91/447 (20%)
		TM helix 1	178..202	CDD:410628	5/25 (20%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	8/21 (38%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	7/26 (27%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	10/24 (42%)
galr1b	NP_001314772.1	7tmA_Gal1_R	34..315	CDD:320226	93/466 (20%)
		TM helix 1	35..61	CDD:320226	7/43 (16%)
		TM helix 2	70..96	CDD:320226	11/25 (44%)
		TM helix 3	108..138	CDD:320226	13/29 (45%)
		TM helix 4	150..170	CDD:320226	4/19 (21%)
		TM helix 5	198..227	CDD:320226	9/118 (8%)
		TM helix 6	241..271	CDD:320226	10/30 (33%)
		TM helix 7	283..308	CDD:320226	10/24 (42%)