Protein Alignment CCKLR-17D1 and npffr1l3

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_073770173.1
• Gene: npffr1l3 / 561324
• ZFINID: ZDB-GENE-070424-44
• Length: 458
• Species: Danio rerio
• Alignment Length: 541
• Identity: 131/541 - (24%)
• Similarity: 194/541 - (35%)
• Gaps: 216/541 - (39%)

  Fly   127 GLELDLGLDLDLNLDMDLAT-TPSSSTLAPAVTVRTPGNRSVVRVSADVPIWVVPCYSAILLCAV 190
            ||..|:.:.:..|:.....| ..:|||:|..:.  :|..:..:..:|...:    .|..|.|..:
Zfish    20 GLWADISICVFSNIHCTNQTNVTNSSTMAGIIL--SPYYQHSLPTAALFTL----AYLFIFLLCL 78

  Fly   191 VGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQ 255
            :||.||.:.:::||.|||:||:|:||||:||:|:|:||:|.|||..|:..:.|...:|||....|
Zfish    79 MGNALVCVIVLRNRHMRTVTNIFILNLAVSDLLVGIFCIPTTLVDNLITGWPFSNTVCKLSGLVQ 143

  Fly   256 AASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFSQLMPT- 319
            ..||:.|.:|||||:.:|:..|.:|.:.:.  |:..|...|..|||.:|..|.|    |.||.|
Zfish   144 GMSVSASVFTLVAIAVDRFRCIVYPFKPKL--TLFIAKVSIGTIWLLALTIMFP----SVLMLTV 202

  Fly   320 ----------------SRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRT 368
                            :.| |..|.|.||...:  .:.|...|.:.:.|:||..:...|..|...
Zfish   203 EQERAHFMIYNDDYNNTYP-LYSCYETWPDPEM--RKIYTTVLFIHIYVIPLALIMLMYGRIGAK 264

  Fly   369 LYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQY 433
            ||                      ||||:|                             |.::|
Zfish   265 LY----------------------SAAVSE-----------------------------HANAQ- 277

  Fly   434 YYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHR 498
                                 |:|
Zfish   278 ---------------------GKR----------------------------------------- 280

  Fly   499 MRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICW 563
                                                          |.||||||.::.|.|.:.|
Zfish   281 ----------------------------------------------KIRVVKMLIMVALLFMLSW 299

  Fly   564 TPLYVINTMTMLLGPTVYEYVGYTSISFL--------QLLAYSSSCCNPITYCFMNASFRRAFVD 620
            .||:   |:.||   |.|.:....|:..|        ..||:|:|..|||.|.:.|.:|:|.|..
Zfish   300 LPLW---TLMML---TDYGHPDNDSLEILTSYIFPLSHWLAFSNSSVNPIIYGYFNENFKRGFQA 358

  Fly   621 TFKGMRVCERLCAPCCFWRRR 641
            .|:         ...||.|||
Zfish   359 VFQ---------RQACFRRRR 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	113/465 (24%)
		TM helix 1	178..202	CDD:410628	7/23 (30%)
		TM helix 2	211..233	CDD:410628	13/21 (62%)
		TM helix 3	249..271	CDD:410628	11/21 (52%)
		TM helix 4	294..310	CDD:410628	6/15 (40%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	10/32 (31%)
npffr1l3	XP_073770173.1	None