Protein Alignment CCKLR-17D1 and ednrbb

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_073769422.1
• Gene: ednrbb / 560081
• ZFINID: ZDB-GENE-081105-182
• Length: 427
• Species: Danio rerio
• Alignment Length: 540
• Identity: 103/540 - (19%)
• Similarity: 172/540 - (31%)
• Gaps: 225/540 - (41%)

  Fly   136 LDLNLDMDLATTPSSSTLAPAVTVRTPGNRSVVRVSA-----------DVPIWVVPCY---SAIL 186
            |.:.|.:.|..| :|..|:.|.|. .||:.:..|:.|           ..|:.:...:   |:::
Zfish    22 LSVILLLSLCFT-ASWRLSNAQTA-DPGSAAHTRLKAPNATENRGPVCSAPVRIKDVFKYISSVV 84

  Fly   187 LCAV-----VGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGEL 246
            .|.|     :||:.::..:.:::.||...|:.:.:||:.|||..|..:||.:...|...:.||.:
Zfish    85 SCVVFLLGMLGNITLLTIIKEHKCMRKGPNIVIGSLALGDILHIVIGLPVNVYKILAVDWPFGVV 149

  Fly   247 LCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSR-------TWQTINHANKIIAIIWLGSL 304
            .|||:.|.|..||.::..:|..:|.:||..:..  |||       .|..|.     :.:||:.|.
Zfish   150 FCKLVPFIQKTSVGITVLSLCVLSIDRYRVVSS--RSRIKGPSFPKWTLIK-----LCVIWVISA 207

  Fly   305 VCMTPIA-AFSQL-MPTSRPGLRKCREQWPADSLNYERAYNLFLDLALL----VLPLLALSFTYL 363
            ....|.| ||.|: |......||.|... |..:..:.:.|.:..|..||    |.||...:..|.
Zfish   208 FLAAPEAVAFDQITMDYRGEHLRICLLH-PVQNNAFMQFYKVAKDWWLLLFYFVFPLSCTAVFYS 271

  Fly   364 FITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHH 428
            .:|..:
Zfish   272 LMTWRI----------------------------------------------------------- 277

  Fly   429 HHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECC 493
                                                     ||.||
Zfish   278 -----------------------------------------LRVQQ------------------- 282

  Fly   494 SRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLE 558
            |.:|:.|:|                                          ::.|.:.:|.|||.
Zfish   283 SALHKHRKQ------------------------------------------RREVARTVFCLVLV 305

  Fly   559 FFICWTPLYVINTMTMLL----GP---------TVYEYVGYTSISFLQLLAYSSSCCNPITYCFM 610
            |.:||.||::...:.|:|    .|         .|.:|:|..       :|..:||.||:....:
Zfish   306 FAVCWFPLHLSRILRMILYDERDPDRCRLLSTFLVLDYIGLN-------MASINSCINPVALYVV 363

  Fly   611 NASFRRAFVDTFKGMRVCER 630
            :..::..|.:..  .|.|.|
Zfish   364 SKRYKNYFREAL--WRCCTR 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	86/474 (18%)
		TM helix 1	178..202	CDD:410628	5/31 (16%)
		TM helix 2	211..233	CDD:410628	9/21 (43%)
		TM helix 3	249..271	CDD:410628	7/21 (33%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	7/26 (27%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	5/24 (21%)
ednrbb	XP_073769422.1	None