Protein Alignment CCKLR-17D1 and npffr1l1

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001165167.1
• Gene: npffr1l1 / 559950
• ZFINID: ZDB-GENE-091118-18
• Length: 398
• Species: Danio rerio
• Alignment Length: 525
• Identity: 111/525 - (21%)
• Similarity: 175/525 - (33%)
• Gaps: 230/525 - (43%)

  Fly   171 SADVPIWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVG 235
            ||.:.:..:..|..:||..||||.||.|.:::||.||::||:|:||||:||:|:|:||:|.||:.
Zfish    27 SAGMAVSYILSYLLVLLLCVVGNGLVCLVVIRNRNMRSVTNLFILNLAVSDLLVGIFCVPTTLID 91

  Fly   236 TLLRHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAI-- 298
            :|:..:.|.::.|.:....|..||:.|.:|||||:.:|:..|.:|...|    :.....:.||
Zfish    92 SLISGWPFSQITCTMSNLVQGMSVSASVFTLVAIAVDRFTGIVYPFHHR----LRPVTALFAIVF 152

  Fly   299 IWLGSLVCMTPIAAF--------------SQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLA 349
            |||.:...:.|.||.              .|:.|     |..|.|.||...:  .|.|...:.:.
Zfish   153 IWLLAFAIIFPSAATLTVIHLDDMYMVQNDQIYP-----LFVCFEDWPRADM--RRVYTTVIFVH 210

  Fly   350 LLVLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLD 414
            :.:.||..:|..|..|...|..:::..|..
Zfish   211 VYLAPLGLISIMYGCIAAKLSSNLQENRLR----------------------------------- 240

  Fly   415 TIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGG 479
                                       |:||:
Zfish   241 ---------------------------SRRRM--------------------------------- 245

  Fly   480 GTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLES 544
                                                                             
Zfish   246 ----------------------------------------------------------------- 245

  Fly   545 KKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVYEYVGYTSISFL--------QLLAYSSSC 601
              :|:|||.::.:.|.:.|.||:.:    |||  |.|:.:....|.||        ..||:.:|.
Zfish   246 --KVIKMLIMVAVLFMVSWLPLWTL----MLL--TDYQDLDRQQIDFLSSYLFPVAHWLAFFNSG 302

  Fly   602 CNPITYCFMNASFRRAFVDTFKGMRVCERLCAPCCFWRRRSKNETNLSVAGNSIALANSVMSSHT 666
            .|||.|.|.|.:|||.|            ..|..|               |...::|:.:..:|.
Zfish   303 VNPIIYGFFNENFRRGF------------QAAVAC---------------GFCSSVASEMRHTHF 340

  Fly   667 ILESP 671
            :|..|
Zfish   341 VLPPP 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	101/464 (22%)
		TM helix 1	178..202	CDD:410628	10/23 (43%)
		TM helix 2	211..233	CDD:410628	13/21 (62%)
		TM helix 3	249..271	CDD:410628	9/21 (43%)
		TM helix 4	294..310	CDD:410628	5/17 (29%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	11/32 (34%)
npffr1l1	NP_001165167.1	7tm_GPCRs	32..319	CDD:475119	101/465 (22%)
		TM helix 1	34..58	CDD:320647	10/23 (43%)
		TM helix 2	67..89	CDD:320647	13/21 (62%)
		TM helix 3	105..127	CDD:320647	9/21 (43%)
		TM helix 4	148..164	CDD:320647	5/15 (33%)
		TM helix 5	201..224	CDD:320647	5/22 (23%)
		TM helix 6	248..270	CDD:320647	7/25 (28%)
		TM helix 7	287..312	CDD:320647	8/24 (33%)