Protein Alignment CCKLR-17D1 and tacr3l

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001243564.1
• Gene: tacr3l / 559201
• ZFINID: ZDB-GENE-061207-19
• Length: 395
• Species: Danio rerio
• Alignment Length: 484
• Identity: 110/484 - (22%)
• Similarity: 171/484 - (35%)
• Gaps: 190/484 - (39%)

  Fly   174 VPIWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLL 238
            |.:|.| .||::|..||.|||:|:..::.::||||:||.||||||.||..:..|...:..:....
Zfish    25 VAVWSV-AYSSVLAVAVFGNLIVIWIILAHKRMRTVTNYFLLNLAFSDASMAAFNTLINFIYATH 88

  Fly   239 RHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAI-IWLG 302
            ..:.|||:.||...|....:|..|.:::.||:.:||.||.|||:.|...|   |.|::.: ||..
Zfish    89 GEWYFGEVYCKFHNFFPVTAVFASIYSMTAIAVDRYMAIIHPLKPRLSAT---ATKVVIVCIWAL 150

  Fly   303 SLVCMTPIAAFSQLMPTSRPGLRK--CREQWP---ADSLNYERAYNLFLDLALLVLPLLALSFTY 362
            :::...|:..:|    |:|...|:  |...||   .||.    .|::.:.:.:.:|||:.:..||
Zfish   151 AVILAFPLCFYS----TTRTMPRRTICYVAWPRPAEDSF----MYHIIVTVLVYMLPLVVMGITY 207

  Fly   363 LFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQH 427
            ..:..||:
Zfish   208 TIVGVTLW--------------------------------------------------------- 215

  Fly   428 HHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGEC 492
                                                               ||.:.|..:.|
Zfish   216 ---------------------------------------------------GGEIPGDSSDN--- 226

  Fly   493 CSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVL 557
                             ||.                            .|.:|::||||:.|:|:
Zfish   227 -----------------YVG----------------------------QLRAKRKVVKMMIVVVV 246

  Fly   558 EFFICWTPLYVINTMTML---LGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFV 619
            .|.:||.|.::...:|.|   |.........|.|:.:   ||.||:..|||.||.:|..||..|.
Zfish   247 TFALCWLPYHIYFIVTGLNKRLNKWKSIQQVYLSVLW---LAMSSTMYNPIIYCCLNGRFRAGFK 308

  Fly   620 DTFKGMRVCERLCAPCCFWRRRSKNETNL 648
            ..|:.          |.|.:..|.:|..|
Zfish   309 RAFRW----------CPFIQVSSYDELEL 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	102/449 (23%)
		TM helix 1	178..202	CDD:410628	10/23 (43%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	6/21 (29%)
		TM helix 4	294..310	CDD:410628	3/16 (19%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	11/24 (46%)
tacr3l	NP_001243564.1	7tm_GPCRs	26..307	CDD:475119	102/451 (23%)
		TM helix 1	28..52	CDD:320669	11/24 (46%)
		TM helix 2	61..83	CDD:320669	10/21 (48%)
		TM helix 3	99..121	CDD:320669	6/21 (29%)
		TM helix 4	142..158	CDD:320669	2/15 (13%)
		TM helix 5	185..208	CDD:320669	5/26 (19%)
		TM helix 6	238..260	CDD:320669	9/21 (43%)
		TM helix 7	275..300	CDD:320669	11/27 (41%)