Protein Alignment CCKLR-17D1 and tacr3a

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001243567.1
• Gene: tacr3a / 555482
• ZFINID: ZDB-GENE-090312-106
• Length: 399
• Species: Danio rerio
• Alignment Length: 492
• Identity: 115/492 - (23%)
• Similarity: 174/492 - (35%)
• Gaps: 180/492 - (36%)

  Fly   174 VPIWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLL 238
            |.:|.| .||:||..||.|||:|:..::.::||||:||.||||||.||..:..|...:..|....
Zfish    25 VALWSV-AYSSILAIAVFGNLIVMWIILAHKRMRTVTNYFLLNLAFSDASMAAFNTLINFVYATH 88

  Fly   239 RHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAI-IWLG 302
            ..:.|||..||...|....||..|.:::.||:.:||.||.|||:.|...|   |.|:|.: ||:.
Zfish    89 GDWYFGEAYCKFHNFFPVTSVFASIYSMSAIAVDRYMAIIHPLKPRLSAT---ATKVIIVCIWVL 150

  Fly   303 SLVCMTPIAAFSQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITR 367
            ::|...|:..||.:....:..|  |...||..|.: ...|::.:.:.:.||||:.:...|..:..
Zfish   151 AVVLAFPLCFFSTIKKLPKRTL--CYVAWPRPSED-PFMYHIIVAMLVYVLPLVVMGINYTIVGL 212

  Fly   368 TLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQ 432
            ||:
Zfish   213 TLW-------------------------------------------------------------- 215

  Fly   433 YYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVH 497
                                                          ||.:.|..:.|
Zfish   216 ----------------------------------------------GGEIPGDSSDN-------- 226

  Fly   498 RMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFIC 562
                     .||                               .|.:|::||||:.::|:.|..|
Zfish   227 ---------YQG-------------------------------QLRAKRKVVKMMIIVVVTFAFC 251

  Fly   563 WTPLYVINTMTML---LGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKG 624
            |.|.:|...:|.|   |....:....|.||.:   ||.||:..|||.||.:|:.||..|...|:.
Zfish   252 WLPYHVYFLVTGLNKQLARWKFIQQIYLSIMW---LAMSSTMYNPIIYCCLNSRFRAGFKRVFRW 313

  Fly   625 MRVCERLCAPCCFWRRRSKNETNLSVAGNSIALANSV 661
                      |.|.:....:|..|....:.:|..:|:
Zfish   314 ----------CPFVQVSDYDELELRAMRHKVARQSSM 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	106/444 (24%)
		TM helix 1	178..202	CDD:410628	11/23 (48%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	7/21 (33%)
		TM helix 4	294..310	CDD:410628	5/16 (31%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	12/24 (50%)
tacr3a	NP_001243567.1	7tm_GPCRs	26..307	CDD:475119	106/446 (24%)
		TM helix 1	28..52	CDD:320669	12/24 (50%)
		TM helix 2	61..83	CDD:320669	10/21 (48%)
		TM helix 3	99..121	CDD:320669	7/21 (33%)
		TM helix 4	142..158	CDD:320669	4/15 (27%)
		TM helix 5	185..208	CDD:320669	5/22 (23%)
		TM helix 6	238..260	CDD:320669	9/21 (43%)
		TM helix 7	275..300	CDD:320669	12/27 (44%)