Protein Alignment CCKLR-17D1 and npy7r

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001007219.1
• Gene: npy7r / 449010
• ZFINID: ZDB-GENE-040924-9
• Length: 372
• Species: Danio rerio
• Alignment Length: 530
• Identity: 110/530 - (20%)
• Similarity: 185/530 - (34%)
• Gaps: 201/530 - (37%)

  Fly   109 VGDGVTITGTPGDLLNYSGLELDLGLDLDLNLDMDLATTPSSSTLAPAVTVRTPGNRSVVRVSAD 173
            :|....:.|:...:|:....|..||.|             |.:|..||..       ..:.....
Zfish     1 MGQSDQVNGSEDTVLHDGNQETSLGND-------------SVNTYKPAFV-------DDITKHLS 45

  Fly   174 VPIWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLL 238
            |.|.::..||.|:|..:|||.||:..::..|.|||:||.|:.|||::|:::...|:|.|||.|||
Zfish    46 VQISLILAYSLIILLGLVGNTLVIYMIILYRNMRTVTNYFIANLALADLMVDTVCLPFTLVYTLL 110

  Fly   239 RHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANK--IIAIIWL 301
            ..:.||.::|.::.::||.||.||..||..|:.|||..|...|..|    :|....  ||.:.|.
Zfish   111 DEWKFGAVMCHMVPYSQALSVHVSILTLTIIALERYRCIVFHLGQR----LNRCTSFIIIGLTWA 171

  Fly   302 GSLVCMTPIAAFSQL----MPTSRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTY 362
            .:.:...|:|.|.:.    :|.....:..|.|:||..:......|:|.:.|...|:||..:|:.|
Zfish   172 FAAILAGPLAIFREYRYEEIPYIDLRIAVCSEKWPNGTNRDAVIYSLSMLLLQYVVPLAIISYAY 236

  Fly   363 LFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQH 427
            :.|    ::.::|
Zfish   237 VCI----WIKLKN---------------------------------------------------- 245

  Fly   428 HHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGEC 492
                                                                             
Zfish   246 ----------------------------------------------------------------- 245

  Fly   493 CSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVL 557
                             :||.                      ||....:..:|:..|||.::|:
Zfish   246 -----------------HVSP----------------------SNRNDGIVRRKKTTKMLALVVV 271

  Fly   558 EFFICWTPLYVI---NTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFV 619
            .|.:||.|.::.   :.:.::|....|:.: ||   ...::|..|:..||:.|.:||.::|..|:
Zfish   272 VFAVCWLPFHMFQLASDLDLILKFKEYKLI-YT---LFHIVAMCSTFVNPLLYGWMNQNYRNGFL 332

  Fly   620 DTFKGMRVCE 629
            ..|:    ||
Zfish   333 MFFR----CE 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	93/449 (21%)
		TM helix 1	178..202	CDD:410628	9/23 (39%)
		TM helix 2	211..233	CDD:410628	8/21 (38%)
		TM helix 3	249..271	CDD:410628	9/21 (43%)
		TM helix 4	294..310	CDD:410628	3/17 (18%)
		TM helix 5	340..363	CDD:410628	7/22 (32%)
		TM helix 6	549..571	CDD:410628	8/24 (33%)
		TM helix 7	586..611	CDD:410628	7/24 (29%)
npy7r	NP_001007219.1	7tm_GPCRs	48..331	CDD:475119	94/450 (21%)
		TM helix 1	50..74	CDD:410628	9/23 (39%)
		TM helix 2	83..105	CDD:410628	8/21 (38%)
		TM helix 3	121..143	CDD:410628	9/21 (43%)
		TM helix 4	164..180	CDD:410628	3/15 (20%)
		TM helix 5	214..237	CDD:410628	7/22 (32%)
		TM helix 6	263..285	CDD:410628	8/21 (38%)
		TM helix 7	299..324	CDD:410628	7/28 (25%)