Protein Alignment CCKLR-17D1 and AstA-R1

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Alignment Length: 461
• Identity: 102/461 - (22%)
• Similarity: 164/461 - (35%)
• Gaps: 187/461 - (40%)

  Fly   170 VSADVPIWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLV 234
            ||..||::    :..|....::||.||:|.:|.|::||:.||:.::|||:||||..:||:|.|..
  Fly    73 VSTIVPVF----FGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTAT 133

  Fly   235 GTLLRHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAII 299
            ..:|..:.||.:.||.:|:....:...|.:|||.:|.:|:.|:.||:.|.:.:|..:|...|...
  Fly   134 DYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCA 198

  Fly   300 WLGSLVCMTPIAAFSQLMPTSRPGL--RKC-----REQWPADSLNYERAYNLFLDLALLVLPLLA 357
            |:..:....|:|....:......|.  ..|     .|.|   ||   ..:.:...|:..|.||..
  Fly   199 WITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEEEIW---SL---VGFQVSFFLSSYVAPLTL 257

  Fly   358 LSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHN 422
            :.|.|:.:...|:.|                                |.|
  Fly   258 ICFLYMGMLARLWKS--------------------------------APG--------------- 275

  Fly   423 PHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGA 487
                                                  |..||
  Fly   276 --------------------------------------CKPSA---------------------- 280

  Fly   488 GNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKML 552
                                       |||:                         .|:||.:|:
  Fly   281 ---------------------------ESRK-------------------------GKRRVTRMV 293

  Fly   553 FVLVLEFFICWTPLYVINTMTMLLGPTVYEYVGYTSISFL-----QLLAYSSSCCNPITYCFMNA 612
            .|:||.|.|||.|::||..:..|   .:|   |.:.:|.:     .::||::||.|||.|.|::.
  Fly   294 VVVVLAFAICWLPIHVILVLKAL---NLY---GGSHLSVIIQIISHVVAYTNSCINPILYAFLSD 352

  Fly   613 SFRRAF 618
            :||:||
  Fly   353 NFRKAF 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	96/452 (21%)
		TM helix 1	178..202	CDD:410628	6/23 (26%)
		TM helix 2	211..233	CDD:410628	11/21 (52%)
		TM helix 3	249..271	CDD:410628	6/21 (29%)
		TM helix 4	294..310	CDD:410628	2/15 (13%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	11/21 (52%)
		TM helix 7	586..611	CDD:410628	10/29 (34%)
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	98/457 (21%)
		TM helix 1	76..102	CDD:320224	9/29 (31%)
		TM helix 2	109..135	CDD:320224	13/25 (52%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	3/19 (16%)
		TM helix 5	239..268	CDD:320224	7/31 (23%)
		TM helix 6	284..314	CDD:320224	14/54 (26%)
		TM helix 7	326..351	CDD:320224	9/24 (38%)