Protein Alignment CCKLR-17D1 and AstC-R2

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Alignment Length: 471
• Identity: 89/471 - (18%)
• Similarity: 159/471 - (33%)
• Gaps: 206/471 - (43%)

  Fly   182 YSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISD--ILLGVFCMPVTLVGTLLRHFIFG 244
            |:.:.:..:.||.||:..:::..:|:|:||:::|||||:|  .|:|:   |..|....:.::.||
  Fly   152 YALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGI---PFLLYTMQVGNWPFG 213

  Fly   245 ELLCKLIQFAQAASVAVSSWT----LVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLV 305
            ..:||    |...|.:::|:|    |:.:|.:||.|:|||:.|..::|...:..:.|..|:.|::
  Fly   214 NYMCK----AYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVL 274

  Fly   306 CMTPIAAFSQLMPTSRPGLRKCREQWPADSLNYER-----AYNLFLDLALLVLPLLALSFTYLFI 365
            .|.|:..|:..:.:|. |...|..:|| |:.|...     .|:|.|..|   .||..:...|..:
  Fly   275 LMLPVILFASTVQSSN-GNVSCNIEWP-DTQNSHTDSTFILYSLVLGFA---TPLTFILVFYCLV 334

  Fly   366 TRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHH 430
            .|.|:            :.||:
  Fly   335 IRKLH------------TVGPK------------------------------------------- 344

  Fly   431 SQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSR 495
                                                                             
  Fly   345 ----------------------------------------------------------------- 344

  Fly   496 VHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFF 560
                                                  .:|.|.|  .|.::|.|::..::..:.
  Fly   345 --------------------------------------HKSKEKK--RSHRKVTKLVLTVISAYI 369

  Fly   561 ICWTPLYVINTMTMLLGPTVYEYVGYTSISFLQL--------LAYSSSCCNPITYCFMNASFRRA 617
            .||.|.::.....:...|       ....|.|:|        |:||:|..|||.|.|::.:|:::
  Fly   370 FCWLPHWISQVALISSAP-------QRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKS 427

  Fly   618 FVDTFKGMRVCERLCA 633
            |      |:.|  .||
  Fly   428 F------MKAC--TCA 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	84/454 (19%)
		TM helix 1	178..202	CDD:410628	5/19 (26%)
		TM helix 2	211..233	CDD:410628	10/23 (43%)
		TM helix 3	249..271	CDD:410628	6/25 (24%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	6/27 (22%)
		TM helix 6	549..571	CDD:410628	4/21 (19%)
		TM helix 7	586..611	CDD:410628	12/32 (38%)
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	84/454 (19%)
		TM helix 1	147..173	CDD:320222	5/20 (25%)
		TM helix 2	180..206	CDD:320222	12/28 (43%)
		TM helix 3	217..247	CDD:320222	11/33 (33%)
		TM helix 4	259..281	CDD:320222	5/21 (24%)
		TM helix 5	308..337	CDD:320222	7/31 (23%)
		TM helix 6	352..382	CDD:320222	6/29 (21%)
		TM helix 7	396..421	CDD:320222	10/24 (42%)