Protein Alignment CCKLR-17D1 and Qrfpr

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_937842.1
• Gene: Qrfpr / 310327
• RGDID: 728380
• Length: 433
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 104/504 - (20%)
• Similarity: 174/504 - (34%)
• Gaps: 194/504 - (38%)

  Fly   185 ILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCK 249
            |...|:.||.||:..:.:::.|||:||:|:.:||:||:|:..||:|||::..:...::.|..:||
  Rat    55 IFALALFGNSLVIYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISDKWLGGAFICK 119

  Fly   250 LIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQ-TINHANKIIAIIWLGSLVCMTPIAAF 313
            ::.|.|:.:|.....|:..|:.||:..:.||.:.: || |...|..|:.::||.:::..:|:...
  Rat   120 MVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMK-WQYTTRRAFTILGVVWLAAIIVGSPMWHV 183

  Fly   314 SQLMPTSRPGLRK----CREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMR 374
            .:|.........|    |.|:|.  |..::|.|:.|:.:.|.:|||:.:...|..|...|::..|
  Rat   184 QRLEIKYDFLYEKEHICCLEEWA--SPVHQRIYSTFILVILFLLPLVVMLVLYSKIGYELWIKKR 246

  Fly   375 NERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGH 439
                           ...|:|:
  Rat   247 ---------------VGDSSAL------------------------------------------- 253

  Fly   440 CGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQ 504
                                             |.|:|
  Rat   254 ---------------------------------QTIHG--------------------------- 258

  Fly   505 LQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVI 569
                          |.:|                 |....|||.|.|:..:|..|..||.|.:|:
  Rat   259 --------------KEMS-----------------KIARKKKRAVIMMVTVVALFAACWAPFHVV 292

  Fly   570 NTMTMLLGPTVYEYVGYTS----------ISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKG 624
            :.|.        ||..:..          .:..|.:.:.:|.|||..|.|||.:|::.|
  Rat   293 HMMV--------EYSNFEKEYDDVTIKMVFAVAQTIGFFNSICNPFVYAFMNENFKKNF------ 343

  Fly   625 MRVCERLCAPC-CFWRRRSKNETNLSVAGNSIALANSVMSSHTILESPR 672
                  |.|.| |..:..|.....   .|||   ..|:|.....|..|:
  Rat   344 ------LSAVCYCIVKESSSPARK---PGNS---GISMMQKRAKLSRPQ 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	91/447 (20%)
		TM helix 1	178..202	CDD:410628	6/16 (38%)
		TM helix 2	211..233	CDD:410628	11/21 (52%)
		TM helix 3	249..271	CDD:410628	6/21 (29%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	7/22 (32%)
		TM helix 6	549..571	CDD:410628	8/21 (38%)
		TM helix 7	586..611	CDD:410628	7/34 (21%)
Qrfpr	NP_937842.1	7tmA_QRFPR	46..343	CDD:320333	91/447 (20%)
		TM helix 1	47..73	CDD:320333	6/17 (35%)
		TM helix 2	80..106	CDD:320333	13/25 (52%)
		TM helix 3	118..148	CDD:320333	9/29 (31%)
		TM helix 4	161..182	CDD:320333	5/20 (25%)
		TM helix 5	211..236	CDD:320333	8/24 (33%)
		TM helix 6	266..296	CDD:320333	11/29 (38%)
		TM helix 7	311..336	CDD:320333	7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	356..389		8/31 (26%)