Protein Alignment CCKLR-17D1 and npy4r

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_571515.1
• Gene: npy4r / 30717
• ZFINID: ZDB-GENE-980526-393
• Length: 377
• Species: Danio rerio
• Alignment Length: 506
• Identity: 125/506 - (24%)
• Similarity: 177/506 - (34%)
• Gaps: 207/506 - (40%)

  Fly   141 DMDLATTPSSSTLAPAVTVRTPGNRSVVRVSADVPIW--------VVPCYSAILLCAVVGNLLVV 197
            ||.|.....:|||     .....|.|:..:  |||.|        :|.||..:|:..::||:|::
Zfish     7 DMPLWQALLNSTL-----THNQSNSSLFLL--DVPCWQSSTMTLTLVLCYCLVLILGLLGNILLI 64

  Fly   198 LTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVS 262
            ..::..|....:|::.:.||::||||:.|||:|.|:|.||:.|:|||.|||:|:.|.|..||.||
Zfish    65 CIIMHQRDPPNVTSILIANLSVSDILVSVFCLPFTVVYTLMDHWIFGALLCRLMPFVQCVSVTVS 129

  Fly   263 SWTLVAISCERYYAICHPLRSRTWQ-TINHANKIIAIIWLGSLVCMT--PIAAFS-------QLM 317
            ..:||.|:.||:..|.||   ..|: ::..|...:..:||  |.|:|  |..||.       .|.
Zfish   130 VLSLVLIALERHQLILHP---SGWKPSVPQAYIAVLTVWL--LACVTSLPFLAFHLLTSEPYSLF 189

  Fly   318 PTSRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFG 382
            |.....|:.|.|.||  |.:::.||...|.|.....|||.:...||.|...|
Zfish   190 PAPLSQLQVCLEVWP--SQDHKLAYTTSLLLFQYCCPLLLMLLCYLRIFLRL------------- 239

  Fly   383 SSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLI 447
                               |||.
Zfish   240 -------------------QRRE------------------------------------------ 243

  Fly   448 SGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVS 512
                                :.|..|                   |||
Zfish   244 --------------------RMLERQ-------------------CSR----------------- 252

  Fly   513 DNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMT---- 573
                                 .|.:|.:.:...||:..||..||..|.:||.||...|.:.
Zfish   253 ---------------------NREDEHRRVMHSKRINVMLATLVAAFAVCWLPLNAFNVVADCDQ 296

  Fly   574 --------MLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRR 616
                    .||            .|...|||.||:|.|||.|.|:|::||:
Zfish   297 EVLPVCNHNLL------------FSLCHLLAMSSTCVNPIIYGFLNSNFRK 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	114/470 (24%)
		TM helix 1	178..202	CDD:410628	7/23 (30%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	10/21 (48%)
		TM helix 4	294..310	CDD:410628	5/17 (29%)
		TM helix 5	340..363	CDD:410628	7/22 (32%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	12/24 (50%)
npy4r	NP_571515.1	7tm_GPCRs	43..337	CDD:475119	113/463 (24%)
		TM helix 1	45..69	CDD:320519	7/23 (30%)
		TM helix 2	78..100	CDD:320519	10/21 (48%)
		TM helix 3	116..138	CDD:320519	10/21 (48%)
		TM helix 4	159..175	CDD:320519	5/17 (29%)
		TM helix 5	210..233	CDD:320519	7/22 (32%)
		TM helix 6	268..290	CDD:320519	9/21 (43%)
		TM helix 7	305..330	CDD:320519	14/36 (39%)