Protein Alignment CCKLR-17D1 and npy8br

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_571511.1
• Gene: npy8br / 30713
• ZFINID: ZDB-GENE-980526-208
• Length: 375
• Species: Danio rerio
• Alignment Length: 514
• Identity: 112/514 - (21%)
• Similarity: 183/514 - (35%)
• Gaps: 204/514 - (39%)

  Fly   177 WVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHF 241
            :::..||.:|...:|||..:|:.:.:.:.||.:||:|::||:.||||:.:.|:|||::.||:..:
Zfish    27 FLIVAYSTMLAVGLVGNTCLVVVITRQKEMRNVTNIFIVNLSCSDILVCLVCLPVTIIYTLMDRW 91

  Fly   242 IFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQ-TINHANKIIAIIWLGSLV 305
            |.||.|||:..|.|..||.||.:::|.|:.||:..|.||   ..|: .:.|:...:|:||:.:..
Zfish    92 ILGEALCKVTPFVQCMSVTVSIFSMVLIALERHQLIIHP---TGWKPVVRHSYLAVAVIWIIACF 153

  Fly   306 CMTPIAAFSQLMPTSRPGLRK----------CREQWPADSLNYERAYNLFLDLALLVLPLLALSF 360
            ...|..:|:.|..:....|..          |.||||::...                      .
Zfish   154 ISLPFLSFNILTNSPFHNLSLPFNPFSDHFICIEQWPSEGNR----------------------L 196

  Fly   361 TYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQ 425
            ||   |.||.:                                      ||
Zfish   197 TY---TTTLLL--------------------------------------CQ-------------- 206

  Fly   426 QHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNG 490
                                              ||:..|.:.
Zfish   207 ----------------------------------YCLPLALIL---------------------- 215

  Fly   491 ECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVL 555
            .|..|:.     ::|          ||||.:.:.:         |....|..:..|||..||..:
Zfish   216 VCYFRIF-----LRL----------SRRKDMVERA---------RGGRQKKAKGSKRVNAMLASI 256

  Fly   556 VLEFFICWTPLYVINTMTMLLGPTVYEYVGYTSISFLQ---------LLAYSSSCCNPITYCFMN 611
            |..|.:||.||.|.|        |:::: .:.:|...|         |.|.:|:|.||:.|.|:|
Zfish   257 VAAFALCWLPLNVFN--------TIFDW-NHEAIPVCQHDAIFSACHLTAMASTCVNPVIYGFLN 312

  Fly   612 ASFRRAFVDTFKGMRVCERLCAPC-CFWRRRSKNETNLSVAGNSIA----LANSVMSSH 665
            .:|::..          :.|.:.| |:....|.....||.....|.    |:|...|::
Zfish   313 NNFQKEL----------KSLLSRCRCWGPAESYESFPLSTVSTGITKGSILSNGSASTY 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	102/460 (22%)
		TM helix 1	178..202	CDD:410628	7/23 (30%)
		TM helix 2	211..233	CDD:410628	11/21 (52%)
		TM helix 3	249..271	CDD:410628	9/21 (43%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	1/22 (5%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	10/33 (30%)
npy8br	NP_571511.1	7tmA_NPY4R	26..319	CDD:320519	102/460 (22%)
		TM helix 1	27..53	CDD:320519	7/25 (28%)
		TM helix 2	60..85	CDD:320519	13/24 (54%)
		TM helix 3	98..128	CDD:320519	12/29 (41%)
		TM helix 4	139..160	CDD:320519	5/20 (25%)
		TM helix 5	195..224	CDD:320519	12/166 (7%)
		TM helix 6	244..274	CDD:320519	14/37 (38%)
		TM helix 7	287..312	CDD:320519	8/24 (33%)