Protein Alignment CCKLR-17D1 and Pgr15l

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001100053.1
• Gene: Pgr15l / 296867
• RGDID: 1562685
• Length: 456
• Species: Rattus norvegicus
• Alignment Length: 500
• Identity: 100/500 - (20%)
• Similarity: 177/500 - (35%)
• Gaps: 185/500 - (37%)

  Fly   146 TTPSSSTLAPA--------VTVRTPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLTLVQ 202
            ||.:.:.::.|        ||....||..::     ..|.:...|:.|::.::.||.||....|:
  Rat    40 TTQNGTNISSAEWGGPRGTVTKWLGGNPHIM-----AKIVLTFAYAVIIVISLFGNSLVCQVFVK 99

  Fly   203 NRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVSSWTLV 267
            ::..:..|.:.:.||||||||:.:...|..|...|...::||.::|.:.:|||..|:.||:.||:
  Rat   100 HKETKKSTGLLIFNLAISDILIILLNSPFALARFLSGQWVFGRIMCHVSRFAQYCSLHVSTLTLM 164

  Fly   268 AISCERYYAICHPLRSRTWQTINHANK--IIAIIWLGSLVCMTPIAAFSQLMP-TSRPG-LRK-C 327
            |::.:|:..|.||::.|    :.|:..  ::.:||..::....|.|.:..|.. .:..| :|. |
  Rat   165 AVAMDRHRVILHPMKPR----LTHSQSLFVVGVIWSIAVFLALPHAIYQNLFTLVNMDGDVRSYC 225

  Fly   328 REQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSS 392
            ...:|..|....:..:|...:.|.:||||.:..||..:.:.|::
  Rat   226 LPSFPGPSTLVSKYVDLGTFILLYILPLLVIVGTYSHLGKRLWI--------------------- 269

  Fly   393 SAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRR 457
            ..|:.:|                                          |.|:|::
  Rat   270 QNAIGDA------------------------------------------SARQLMA--------- 283

  Fly   458 HLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLS 522
                          |.|
  Rat   284 --------------HYQ------------------------------------------------ 286

  Fly   523 QPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVYEYVGYT 587
                                 .:|:.::||.::||.|.:||.||   |...:|:.....|.....
  Rat   287 ---------------------KRKKSIRMLILIVLVFAVCWFPL---NFYVVLISSAGVENDSVI 327

  Fly   588 SISFLQLLAYSSSCCNPITYCFMNASFRRAF--VDTFK--GMRVC 628
            ..:| ...|.||:|.||..||::|.|||...  :.:|:  .:.||
  Rat   328 FYAF-HWFAMSSTCYNPFIYCWLNRSFRAKLRSISSFRMQSLFVC 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	89/445 (20%)
		TM helix 1	178..202	CDD:410628	6/23 (26%)
		TM helix 2	211..233	CDD:410628	9/21 (43%)
		TM helix 3	249..271	CDD:410628	9/21 (43%)
		TM helix 4	294..310	CDD:410628	2/17 (12%)
		TM helix 5	340..363	CDD:410628	7/22 (32%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	9/24 (38%)
Pgr15l	NP_001100053.1	7tmA_GPR83	73..357	CDD:320511	90/446 (20%)
		TM helix 1	74..100	CDD:320511	7/25 (28%)
		TM helix 2	107..132	CDD:320511	11/24 (46%)
		TM helix 3	145..175	CDD:320511	11/29 (38%)
		TM helix 4	186..207	CDD:320511	3/20 (15%)
		TM helix 5	237..266	CDD:320511	8/28 (29%)
		TM helix 6	286..316	CDD:320511	12/101 (12%)
		TM helix 7	325..350	CDD:320511	9/25 (36%)