Protein Alignment CCKLR-17D1 and Galr2

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_062045.1
• Gene: Galr2 / 29234
• RGDID: 2657
• Length: 372
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 109/519 - (21%)
• Similarity: 170/519 - (32%)
• Gaps: 206/519 - (39%)

  Fly   178 VVPCYSA-ILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHF 241
            :||.:.| |.|...|||.||:..|::..:..:.||:|:|||.::|:...:.|:|.......|..:
  Rat    27 LVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDW 91

  Fly   242 IFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVC 306
            :||.||||.:.|....::..||:||.|:|.:||.||.:||.||..:|..:|...|.:||..:|:.
  Rat    92 VFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLF 156

  Fly   307 MTPIAAF---SQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRT 368
            ..|..::   |||     ..|..|...|.|..   .||.:|...:...:||:|.||.||   .||
  Rat   157 SGPYLSYYRQSQL-----ANLTVCHPAWSAPR---RRAMDLCTFVFSYLLPVLVLSLTY---ART 210

  Fly   369 LYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQY 433
            |....|....:..||                ||||
  Rat   211 LRYLWRTVDPVTAGS----------------GSQR------------------------------ 229

  Fly   434 YYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHR 498
                                                                             
  Rat   230 ----------------------------------------------------------------- 229

  Fly   499 MRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICW 563
                                                         :|::|.:|:.::.:.|.:||
  Rat   230 ---------------------------------------------AKRKVTRMIIIVAVLFCLCW 249

  Fly   564 TPLYVINTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVC 628
            .|.:.: .:.:..|........|.......|::|::||.|||.|..::..||:.|      .::|
  Rat   250 MPHHAL-ILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGF------RKIC 307

  Fly   629 ERLCAPCCFWRRRSKNETNLSVAGNSI-------------------------ALANSVMSSHTI 667
            ..|..|.   .||:....::...||..                         ||.|...||.|:
  Rat   308 AGLLRPA---PRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPPALPNCTASSRTL 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	95/443 (21%)
		TM helix 1	178..202	CDD:410628	11/24 (46%)
		TM helix 2	211..233	CDD:410628	8/21 (38%)
		TM helix 3	249..271	CDD:410628	7/21 (33%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	9/22 (41%)
		TM helix 6	549..571	CDD:410628	5/21 (24%)
		TM helix 7	586..611	CDD:410628	9/24 (38%)
Galr2	NP_062045.1	7tmA_Gal2_Gal3_R	26..303	CDD:320225	95/443 (21%)
		TM helix 1	27..53	CDD:320225	11/25 (44%)
		TM helix 2	60..86	CDD:320225	9/25 (36%)
		TM helix 3	98..128	CDD:320225	12/29 (41%)
		TM helix 4	140..160	CDD:320225	5/19 (26%)
		TM helix 5	184..213	CDD:320225	13/31 (42%)
		TM helix 6	229..259	CDD:320225	8/170 (5%)
		TM helix 7	271..296	CDD:320225	9/24 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	353..372		6/16 (38%)