Protein Alignment CCKLR-17D1 and Sstr4

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_037168.1
• Gene: Sstr4 / 25555
• RGDID: 3764
• Length: 384
• Species: Rattus norvegicus
• Alignment Length: 502
• Identity: 108/502 - (21%)
• Similarity: 179/502 - (35%)
• Gaps: 189/502 - (37%)

  Fly   147 TPSSSTLAPAVTVRTPG---------NRSVVRV--SADVPIWVVPC-YSAILLCAVVGNLLVVLT 199
            ||::..|....|..|||         ....||.  :....:..:.| |:.:.|..:|||.||:..
  Rat     3 TPATLPLGGEDTTWTPGINASWAPDEEEDAVRSDGTGTAGMVTIQCIYALVCLVGLVGNALVIFV 67

  Fly   200 LVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVSSW 264
            :::..:|:|.||::|||||::|.|. :..:|.......|||:.||.:||:.:......::..|.:
  Rat    68 ILRYAKMKTATNIYLLNLAVADELF-MLSVPFVASAAALRHWPFGAVLCRAVLSVDGLNMFTSVF 131

  Fly   265 TLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFSQLMPTSRPGLRKCRE 329
            .|..:|.:||.|:.||||:.|::..:.|..|...:||.||:...|||.|:...|........|..
  Rat   132 CLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAVFADTRPARGGEAVACNL 196

  Fly   330 QWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSA 394
            .||..:  :...:.::..|...:||:||:...||.|..    .||                   |
  Rat   197 HWPHPA--WSAVFVIYTFLLGFLLPVLAIGLCYLLIVG----KMR-------------------A 236

  Fly   395 AVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHL 459
            ....||.|:|
  Rat   237 VALRAGWQQR------------------------------------------------------- 246

  Fly   460 YCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQP 524
                                                                             
  Rat   247 ----------------------------------------------------------------- 246

  Fly   525 SLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVYEYVGYTSI 589
                     ||        |:|::.:::.::|..|.:||.|.||:..:.:.: .::...|.:.|:
  Rat   247 ---------RR--------SEKKITRLVLMVVTVFVLCWMPFYVVQLLNLFV-TSLDATVNHVSL 293

  Fly   590 SFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLCAPCC 636
                :|:|::||.|||.|.|::.:|||:|      .||   ||..||
  Rat   294 ----ILSYANSCANPILYGFLSDNFRRSF------QRV---LCLRCC 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	92/441 (21%)
		TM helix 1	178..202	CDD:410628	8/24 (33%)
		TM helix 2	211..233	CDD:410628	9/21 (43%)
		TM helix 3	249..271	CDD:410628	2/21 (10%)
		TM helix 4	294..310	CDD:410628	5/15 (33%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	10/24 (42%)
Sstr4	NP_037168.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		7/30 (23%)
		7tmA_SSTR4	44..318	CDD:320639	92/441 (21%)
		TM helix 1	45..71	CDD:320639	8/25 (32%)
		TM helix 2	78..104	CDD:320639	10/26 (38%)
		TM helix 3	115..145	CDD:320639	7/29 (24%)
		TM helix 4	157..179	CDD:320639	8/21 (38%)
		TM helix 5	204..233	CDD:320639	8/32 (25%)
		TM helix 6	248..278	CDD:320639	10/37 (27%)
		TM helix 7	286..311	CDD:320639	11/28 (39%)