Protein Alignment CCKLR-17D1 and Nmbr

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_036931.1
• Gene: Nmbr / 25264
• RGDID: 3181
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 102/548 - (18%)
• Similarity: 192/548 - (35%)
• Gaps: 196/548 - (35%)

  Fly   141 DMDLATTPSSSTLAPAVTVR-----TPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLTL 200
            ::.|.|..|.|.|.|.|...     :.|..:.:.:...:|    ..|..|:...::||:::|...
  Rat     8 NLSLPTEASESELEPEVWENDFLPDSDGTTAELVIRCVIP----SLYLIIISVGLLGNIMLVKIF 68

  Fly   201 VQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVSSWT 265
            :.|..||::.|:|:.|||..|:||.:.|:||.........::||:|.||||...|..||.||.:|
  Rat    69 LTNSTMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFT 133

  Fly   266 LVAISCERYYAICHPLRSRT-----WQTINHANKIIAIIWLGSLVCMTPIAAFSQLM---PTSRP 322
            |.|:|.:||.||.:|:..:|     |.::....     ||:.|::...|.|.||::.   .:...
  Rat   134 LTALSADRYRAIVNPMDMQTSGVVLWTSLKAVG-----IWVVSVLLAVPEAVFSEVARIGSSDNS 193

  Fly   323 GLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPE 387
            ....|......|.| :.:.:::.:.|...::||:.:|..|..|.:||..|..|
  Rat   194 SFTACIPYPQTDEL-HPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIRSAHN------------ 245

  Fly   388 VTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGP 452
                                         :|.::|.|.:
  Rat   246 -----------------------------LPGEYNEHTK-------------------------- 255

  Fly   453 CEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESR 517
                                                                             
  Rat   256 ----------------------------------------------------------------- 255

  Fly   518 RKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVYE 582
                                  |.:|::||:.|::.|.|..|..||.|.:::..........:..
  Rat   256 ----------------------KQMETRKRLAKIVLVFVGCFVFCWFPNHILYLYRSFNYKEIDP 298

  Fly   583 YVGYTSISFL-QLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLCAPCCFWRRRSKNET 646
            .:|:..::.: ::|::|:||.||.....::.|||:.|....            ||..:...:..|
  Rat   299 SLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQL------------CCGQKSYPERST 351

  Fly   647 NLSVAGNSIAL------ANSVMSSHTIL 668
            :..::.:::.:      |.:|:::..:|
  Rat   352 SYLLSSSAVRMTSLKSNAKNVVTNSVLL 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	86/449 (19%)
		TM helix 1	178..202	CDD:410628	5/23 (22%)
		TM helix 2	211..233	CDD:410628	11/21 (52%)
		TM helix 3	249..271	CDD:410628	11/21 (52%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	4/22 (18%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	6/25 (24%)
Nmbr	NP_036931.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		4/11 (36%)
		7tm_GPCRs	44..335	CDD:475119	87/454 (19%)
		TM helix 1	46..70	CDD:410628	6/27 (22%)
		TM helix 2	79..101	CDD:410628	11/21 (52%)
		TM helix 3	117..139	CDD:410628	11/21 (52%)
		TM helix 4	162..178	CDD:410628	3/20 (15%)
		TM helix 5	210..233	CDD:410628	4/22 (18%)
		TM helix 6	265..287	CDD:410628	7/21 (33%)
		TM helix 7	303..328	CDD:410628	6/24 (25%)