Protein Alignment CCKLR-17D1 and Pgr15l

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001028533.1
• Gene: Pgr15l / 245526
• MGIID: 2676330
• Length: 456
• Species: Mus musculus
• Alignment Length: 456
• Identity: 92/456 - (20%)
• Similarity: 164/456 - (35%)
• Gaps: 172/456 - (37%)

  Fly   182 YSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGEL 246
            |:.|::.::.||.||....|:::.::..|.:.:.||||||||:.:...|..|...|...::||.:
Mouse    79 YAVIIVISLFGNSLVCQVFVKHKEIKKSTGLLIFNLAISDILIILLNSPFALARFLSGQWVFGRI 143

  Fly   247 LCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHAN--KIIAIIWLGSLVCMTP 309
            :|.:.:|||..|:.||:.||:|::.:|:..|.||::.|    :.|:.  .::|:||..::....|
Mouse   144 MCHVSRFAQYCSLHVSTLTLMAVAMDRHRVILHPMKPR----LTHSQCLFVVAMIWSIAVFLALP 204

  Fly   310 IAAFSQLMP-TSRPGLRK--CREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYV 371
            .|.:..|.. .:..|..:  |...:|..|:...:..:|...:.|.:||||.:..||..:.:.|::
Mouse   205 HAIYQNLFTLVNMDGDTRSYCLPSFPGPSILVSKYVDLGTFILLYILPLLVIVVTYSHLGKRLWI 269

  Fly   372 SMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYD 436
                                 ..|:.:|
Mouse   270 ---------------------QNAIGDA------------------------------------- 276

  Fly   437 YGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQ 501
                 |.|:|::                       |.|
Mouse   277 -----SARQLMA-----------------------HYQ--------------------------- 286

  Fly   502 QMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPL 566
                                                      .:|:.::||.::||.|.:||.||
Mouse   287 ------------------------------------------KRKKSIRMLILIVLVFAVCWFPL 309

  Fly   567 YVINTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAF--VDTFK--GMRV 627
               |...:|:.....|.......:| ...|.||:|.||..||::|.|||...  :.:|:  .:.|
Mouse   310 ---NFYVVLISSAGVENDSVLFYAF-HWFAMSSTCYNPFIYCWLNRSFRAKLRSISSFRMQSLFV 370

  Fly   628 C 628
            |
Mouse   371 C 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	89/440 (20%)
		TM helix 1	178..202	CDD:410628	6/19 (32%)
		TM helix 2	211..233	CDD:410628	9/21 (43%)
		TM helix 3	249..271	CDD:410628	9/21 (43%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	7/22 (32%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	9/24 (38%)
Pgr15l	NP_001028533.1	7tmA_GPR83	73..357	CDD:320511	89/440 (20%)
		TM helix 1	74..100	CDD:320511	7/20 (35%)
		TM helix 2	107..132	CDD:320511	11/24 (46%)
		TM helix 3	145..175	CDD:320511	11/29 (38%)
		TM helix 4	186..207	CDD:320511	4/20 (20%)
		TM helix 5	237..266	CDD:320511	8/28 (29%)
		TM helix 6	286..316	CDD:320511	12/101 (12%)
		TM helix 7	325..350	CDD:320511	9/25 (36%)