Protein Alignment CCKLR-17D1 and Qrfprl

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_780733.2
• Gene: Qrfprl / 243407
• MGIID: 2441881
• Length: 416
• Species: Mus musculus
• Alignment Length: 458
• Identity: 90/458 - (19%)
• Similarity: 160/458 - (34%)
• Gaps: 178/458 - (38%)

  Fly   185 ILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCK 249
            |...|:.||.|||..:.:::.|||:||:|:.:||:||:|:..||:|||::..:...::.|..:||
Mouse    54 IFALALFGNALVVYVVTRSKAMRTVTNIFICSLALSDLLIVFFCIPVTMLQNVSDTWLGGAFICK 118

  Fly   250 LIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFS 314
            ::.|.|..::.....|:..|:.||:..:.||.:.:...|...|..::.::||.:::..:|:....
Mouse   119 MVPFVQCTAIVTEILTMTCIAVERHQGLVHPFKMKRQYTNQRAFTMLGVVWLVAIIIGSPMWHVQ 183

  Fly   315 QLMPTSRPGLRK----CREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRN 375
            :|.........|    |.|:|  .|..:::.|..|:.:.|.:||||.||..|..|...|::
Mouse   184 RLEIKYDFLYEKEHICCLEEW--SSPVHQKIYTTFILVTLFLLPLLLLSVLYGKIGYELWI---- 242

  Fly   376 ERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHC 440
                                                                             
Mouse   243 ----------------------------------------------------------------- 242

  Fly   441 GSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQL 505
              |:|:                                         |:|.....:|....
Mouse   243 --KKRI-----------------------------------------GDGSVLRTIHGKEM---- 260

  Fly   506 QQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVIN 570
                                             .|....|||.|.|:..:|:.|.:||.|.::::
Mouse   261 ---------------------------------FKIARKKKRAVIMMVTVVVLFAVCWAPFHIVH 292

  Fly   571 TMTMLLGPTVYEYVGYTS----------ISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGM 625
            .|        .||..:..          .:.:|::.:.:|.||||.|..||.:|::.||..
Mouse   293 MM--------IEYSNFEKEYDEVTIKMIFAIVQIIGFFNSICNPIIYALMNENFKKNFVSA---- 345

  Fly   626 RVC 628
             ||
Mouse   346 -VC 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	86/446 (19%)
		TM helix 1	178..202	CDD:410628	7/16 (44%)
		TM helix 2	211..233	CDD:410628	11/21 (52%)
		TM helix 3	249..271	CDD:410628	5/21 (24%)
		TM helix 4	294..310	CDD:410628	2/15 (13%)
		TM helix 5	340..363	CDD:410628	9/22 (41%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	7/34 (21%)
Qrfprl	NP_780733.2	7tmA_QRFPR	45..342	CDD:320333	86/446 (19%)
		TM helix 1	46..72	CDD:320333	7/17 (41%)
		TM helix 2	79..105	CDD:320333	13/25 (52%)
		TM helix 3	117..147	CDD:320333	8/29 (28%)
		TM helix 4	160..181	CDD:320333	4/20 (20%)
		TM helix 5	210..235	CDD:320333	10/24 (42%)
		TM helix 6	265..295	CDD:320333	11/37 (30%)
		TM helix 7	310..335	CDD:320333	7/24 (29%)