Protein Alignment CCKLR-17D1 and Sstr4

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_033245.2
• Gene: Sstr4 / 20608
• MGIID: 105372
• Length: 385
• Species: Mus musculus
• Alignment Length: 510
• Identity: 109/510 - (21%)
• Similarity: 179/510 - (35%)
• Gaps: 210/510 - (41%)

  Fly   151 STLAPAV--TVRTPGNRSVVRVSADVPIW---------------------VVPC-YSAILLCAVV 191
            :||.|.|  |..|||      ::|.   |                     .:.| |:.:.|..:|
Mouse     5 ATLPPGVEDTTWTPG------INAS---WAPDEEEEDAMGSDGTGTAGMVTIQCIYALVCLVGLV 60

  Fly   192 GNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQA 256
            ||.||:..:::..:|:|.||::|||||::|.|. :..:|.......|||:.||.:||:.:.....
Mouse    61 GNALVIFVILRYAKMKTATNIYLLNLAVADELF-MLSVPFVASAAALRHWPFGAVLCRAVLSVDG 124

  Fly   257 ASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFSQLMPTSR 321
            .::..|.:.|..:|.:||.|:.||||:.|::..:.|..|...:||.||:...|||.|:...|...
Mouse   125 LNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAVFADTRPARG 189

  Fly   322 PGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGP 386
            .....|...||..:  :...:.::..|...:||:||:...||.|..    .||
Mouse   190 GEAVACNLHWPHPA--WSAVFVIYTFLLGFLLPVLAIGLCYLLIVG----KMR------------ 236

  Fly   387 EVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGG 451
                   |....||.|:|
Mouse   237 -------AVALRAGWQQR----------------------------------------------- 247

  Fly   452 PCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNES 516
                                                                             
Mouse   248 ----------------------------------------------------------------- 247

  Fly   517 RRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVY 581
                             ||        |:|::.:::.::|..|.:||.|.||:..:.:.: .::.
Mouse   248 -----------------RR--------SEKKITRLVLMVVTVFVLCWMPFYVVQLLNLFV-TSLD 286

  Fly   582 EYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLCAPCC 636
            ..|.:.|:    :|:|::||.|||.|.|::.:|||:|      .||   ||..||
Mouse   287 ATVNHVSL----ILSYANSCANPILYGFLSDNFRRSF------QRV---LCLRCC 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	93/462 (20%)
		TM helix 1	178..202	CDD:410628	8/24 (33%)
		TM helix 2	211..233	CDD:410628	9/21 (43%)
		TM helix 3	249..271	CDD:410628	2/21 (10%)
		TM helix 4	294..310	CDD:410628	5/15 (33%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	10/24 (42%)
Sstr4	NP_033245.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		10/40 (25%)
		7tmA_SSTR4	45..319	CDD:320639	92/441 (21%)
		TM helix 1	46..72	CDD:320639	8/25 (32%)
		TM helix 2	79..105	CDD:320639	10/26 (38%)
		TM helix 3	116..146	CDD:320639	7/29 (24%)
		TM helix 4	158..180	CDD:320639	8/21 (38%)
		TM helix 5	205..234	CDD:320639	8/32 (25%)
		TM helix 6	249..279	CDD:320639	10/37 (27%)
		TM helix 7	287..312	CDD:320639	11/28 (39%)