DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCKLR-17D1 and R13H4.7

DIOPT Version :9

Sequence 1:	NP_001097021.1	Gene:	CCKLR-17D1 / 32860	FlyBaseID:	FBgn0259231	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_001256380.1	Gene:	R13H4.7 / 187874	WormBaseID:	WBGene00011265	Length:	347	Species:	Caenorhabditis elegans

Alignment Length:	265	Identity:	69/265 - (26%)
Similarity:	111/265 - (41%)	Gaps:	72/265 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 ILLCAVVGNLLVVLTLVQNRRMRTITNV----FLLNLAISDILL----GVFCMPVTLVGTLLRHF 241
            :||..:||..|..|.:....||  :..:    ||::.|::||||    |::  |..::  |.::.
Worm    12 LLLFGIVGCALYGLIVCSMWRM--VNEIVGFRFLISQALTDILLMIQFGIW--PGIVI--LTQNE 70

  Fly   242 IFGE-------LLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTW-QTINHANKII-- 296
            |..|       :......:|......|.:|:.:|       |:..|    .| :|:.|...|:
Worm    71 IINESWRWNIHIYLDFTWWAMVYHYTVIAWSRLA-------AVQWP----NWFRTLPHGTSIMIC 124

  Fly   297 AIIW----LGSLV-----CMTPIAAFSQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALLV 352
            ||.|    |.|||     ..||:.    ..|| |.|:   ...|....|:....|.:..::.|:|
Worm   125 AIPWFTGLLQSLVEHQFDWFTPLF----YSPT-RYGM---HSDWEKYELSGTNTYYMVCNVILMV 181

  Fly   353 L--PLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDT 415
            :  ||..|:...||..:|    .||.:..:..|..| ::|||.||     .||:.      |::|
Worm   182 VPFPLYVLALAVLFQRQT----SRNMQLRSKYSHAP-ISTSSYAA-----QQRQL------SIET 230

  Fly   416 --IVP 418
              :||
Worm   231 RLLVP 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_4	185..>308	CDD:304433	37/149 (25%)
CCKLR-17D1	NP_001097021.1	7tm_1	192..>380	CDD:278431	53/216 (25%)
R13H4.7	NP_001256380.1	7tm_GPCRs	6..283	CDD:333717	69/265 (26%)
		TM helix 1	6..29	CDD:320095	6/16 (38%)
		TM helix 2	40..63	CDD:320095	9/24 (38%)
		TM helix 3	79..100	CDD:320095	2/20 (10%)
		TM helix 4	122..143	CDD:320095	7/20 (35%)
		TM helix 5	169..192	CDD:320095	6/22 (27%)
		TM helix 7	258..283	CDD:320095
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24238
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100