Protein Alignment CCKLR-17D1 and npr-33

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_510612.1
• Gene: npr-33 / 185141
• WormBaseID: WBGene00009278
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 456
• Identity: 92/456 - (20%)
• Similarity: 156/456 - (34%)
• Gaps: 172/456 - (37%)

  Fly   185 ILLCA-VVGNLLVVLTLVQNRR-MRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELL 247
            |::|| |:||:.:|..::.:|: |.:..|.|||||||:|:...:||.|..::..:.|.::.....
 Worm    68 IIICAGVIGNIFIVFVILMDRKLMSSSVNQFLLNLAIADLGNLIFCSPDAILVLIDRGWLLPNFA 132

  Fly   248 CKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAA 312
            |.|::|.|...:..|....:||..||:.|||.|:|.:.:.| .....::|.:|..:....:|...
 Worm   133 CHLLRFLQEYFLYASVLLQMAIGVERFLAICSPMRMQRFST-KTTISVLAGVWCVAACFASPYFL 196

  Fly   313 FSQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALL-VLPLLALSFTYLFITRTLYVSMRNE 376
            :..::...   |..|  .|...| :..|.|..:.:|.:| .:||:.|:..|..:.|.|:.:..|.
 Worm   197 YQGIVFHK---LYFC--FWKGIS-HKTRTYFKYCELIVLYAIPLVFLTTLYSIMCRVLWGNEDNH 255

  Fly   377 RAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCG 441
            ...|                                                 |||
 Worm   256 NIAN-------------------------------------------------HSQ--------- 262

  Fly   442 SKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQ 506
                                 :.|.:|
 Worm   263 ---------------------QEAILK-------------------------------------- 268

  Fly   507 QQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINT 571
                                      ||||           |||||.:.:|.:|:|:||:.|:..
 Worm   269 --------------------------LRRS-----------VVKMLIISMLLYFLCYTPIQVLFM 296

  Fly   572 MTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLCAPCC 636
            :..:|..:| :...:..: .|.:|:..||..|||.|......||....|...|      :.:.||
 Worm   297 LEKILDHSV-QLPQWLRL-LLNVLSVMSSSTNPIVYIICCRHFRLRLRDVAAG------ISSFCC 353

  Fly   637 F 637
            :
 Worm   354 W 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	88/435 (20%)
		TM helix 1	178..202	CDD:410628	7/17 (41%)
		TM helix 2	211..233	CDD:410628	12/21 (57%)
		TM helix 3	249..271	CDD:410628	6/21 (29%)
		TM helix 4	294..310	CDD:410628	2/15 (13%)
		TM helix 5	340..363	CDD:410628	7/23 (30%)
		TM helix 6	549..571	CDD:410628	10/21 (48%)
		TM helix 7	586..611	CDD:410628	8/24 (33%)
npr-33	NP_510612.1	7tm_classA_rhodopsin-like	62..334	CDD:410626	86/428 (20%)
		TM helix 1	62..87	CDD:410626	7/18 (39%)
		TM helix 2	94..121	CDD:410626	12/26 (46%)
		TM helix 3	133..163	CDD:410626	10/29 (34%)
		TM helix 4	175..194	CDD:410626	2/18 (11%)
		TM helix 5	218..243	CDD:410626	8/24 (33%)
		TM helix 6	268..298	CDD:410626	16/104 (15%)
		TM helix 7	309..334	CDD:410626	8/25 (32%)