Protein Alignment CCKLR-17D1 and Npy6r

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_035065.1
• Gene: Npy6r / 18169
• MGIID: 1098590
• Length: 371
• Species: Mus musculus
• Alignment Length: 461
• Identity: 105/461 - (22%)
• Similarity: 162/461 - (35%)
• Gaps: 201/461 - (43%)

  Fly   182 YSAILLCAVVGNL-LVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGE 245
            |:.||:..:.||| |:::...:.|..:.:||:.:.||::||||:.|.|:|.|::.||:.|::||.
Mouse    42 YTVILIMGIFGNLSLIIIIFKKQREAQNVTNILIANLSLSDILVCVMCIPFTVIYTLMDHWVFGN 106

  Fly   246 LLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQ-TINHANKIIAIIWLGSLVCMTP 309
            .:|||..:.|:.||:||.::||.|:.|||..|.:|   |.|: .:.||...|.:|||.||....|
Mouse   107 TMCKLTSYVQSVSVSVSIFSLVLIAIERYQLIVNP---RGWKPRVAHAYWGIILIWLISLTLSIP 168

  Fly   310 IAAFSQLMPTSRPGLR------------KCREQWPADSLNYERAYNLFLDLALLVL----PLLAL 358
            :  |.....|:.|...            .|.|.||: .||     .|....:|.:|    ||..:
Mouse   169 L--FLSYHLTNEPFHNLSLPTDIYTHQVACVEIWPS-KLN-----QLLFSTSLFMLQYFVPLGFI 225

  Fly   359 SFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNP 423
            ...||.|
Mouse   226 LICYLKI---------------------------------------------------------- 232

  Fly   424 HQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAG 488
                                               :.|:|.      |.:|::
Mouse   233 -----------------------------------VLCLRK------RTRQVD------------ 244

  Fly   489 NGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKS-LESKKRVVKML 552
                                        |||                  |.|| |...|||..||
Mouse   245 ----------------------------RRK------------------ENKSRLNENKRVNVML 263

  Fly   553 FVLVLEFFICWTPLYVINTM-----TMLLGPTVYEYVGYTSISFL--QLLAYSSSCCNPITYCFM 610
            ..:|:.|..||.||.:.|.:     .||:.       .:..:.|:  .|:|..|:|.||:.|.|:
Mouse   264 ISIVVTFGACWLPLNIFNVIFDWYHEMLMS-------CHHDLVFVVCHLIAMVSTCINPLFYGFL 321

  Fly   611 NASFRR 616
            |.:|::
Mouse   322 NKNFQK 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	105/461 (23%)
		TM helix 1	178..202	CDD:410628	7/20 (35%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	10/21 (48%)
		TM helix 4	294..310	CDD:410628	6/15 (40%)
		TM helix 5	340..363	CDD:410628	5/26 (19%)
		TM helix 6	549..571	CDD:410628	8/21 (38%)
		TM helix 7	586..611	CDD:410628	9/26 (35%)
Npy6r	NP_035065.1	7tm_GPCRs	42..329	CDD:475119	105/461 (23%)
		TM helix 1	42..63	CDD:320518	7/20 (35%)
		TM helix 2	72..94	CDD:320518	10/21 (48%)
		TM helix 3	110..132	CDD:320518	10/21 (48%)
		TM helix 4	153..169	CDD:320518	6/15 (40%)
		TM helix 5	207..230	CDD:320518	5/22 (23%)
		TM helix 6	260..282	CDD:320518	8/21 (38%)
		TM helix 7	297..322	CDD:320518	9/24 (38%)