Protein Alignment CCKLR-17D1 and Gpr83

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_030099918.1
• Gene: Gpr83 / 14608
• MGIID: 95712
• Length: 480
• Species: Mus musculus
• Alignment Length: 519
• Identity: 99/519 - (19%)
• Similarity: 165/519 - (31%)
• Gaps: 236/519 - (45%)

  Fly   178 VVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFI 242
            ::..||..::.::.||:||...:.:|:||.:.|::|::|||::||::.:...|.|||..:...::
Mouse    74 LIVAYSFTIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWV 138

  Fly   243 FGELLCKLIQFAQAASVAVSSWTLVAISCERYY-------------------------------- 275
            ||:.:|.:.:|||..|:.||:.||.||:.:|:.
Mouse   139 FGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQGLELQKMVRPRGDGGELRSPSVTFVPSSLCPA 203

  Fly   276 -------------------------AICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFSQ 315
                                     .|.|||:.|.  :|......||:||:.:.....|.|...:
Mouse   204 LFTCKRPWDFQESQSLHDTLFPPLEVIMHPLKPRI--SITKGVIYIAVIWVMATFFSLPHAICQK 266

  Fly   316 L--MPTSRPGLRK-CREQW--PADSLNYERAYNLFLDLA----LLVLPLLALSFTYLFITRTLYV 371
            |  ...|...:|. |...:  |||      .:..:||||    |.:|||..:|..|..:.:.|::
Mouse   267 LFTFKYSEDIVRSLCLPDFPEPAD------LFWKYLDLATFILLYLLPLFIISVAYARVAKKLWL 325

  Fly   372 SMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYD 436
                                                  |.::..:...|:
Mouse   326 --------------------------------------CNTIGDVTTEQY--------------- 337

  Fly   437 YGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQ 501
                                                                             
Mouse   338 ----------------------------------------------------------------- 337

  Fly   502 QMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPL 566
                                         ..|||        .||..||||.::|:.|.:||.||
Mouse   338 -----------------------------LALRR--------KKKTTVKMLVLVVVLFALCWFPL 365

  Fly   567 YVINTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCER 630
               |...:||.............:| ...|.||:|.||..||::|.:||   |:....:.:|:|
Mouse   366 ---NCYVLLLSSKAIHTNNALYFAF-HWFAMSSTCYNPFIYCWLNENFR---VELKALLSMCQR 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	96/505 (19%)
		TM helix 1	178..202	CDD:410628	6/23 (26%)
		TM helix 2	211..233	CDD:410628	7/21 (33%)
		TM helix 3	249..271	CDD:410628	10/21 (48%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	9/26 (35%)
		TM helix 6	549..571	CDD:410628	10/21 (48%)
		TM helix 7	586..611	CDD:410628	9/24 (38%)
Gpr83	XP_030099918.1	7tmA_GPR83	72..413	CDD:320511	97/508 (19%)
		TM helix 1	73..99	CDD:320511	6/24 (25%)
		TM helix 2	106..131	CDD:320511	10/24 (42%)
		TM helix 3	144..231	CDD:320511	12/86 (14%)
		TM helix 4	242..263	CDD:320511	5/20 (25%)
		TM helix 5	293..322	CDD:320511	10/28 (36%)
		TM helix 6	342..372	CDD:320511	14/40 (35%)
		TM helix 7	381..406	CDD:320511	9/25 (36%)