Protein Alignment CCKLR-17D1 and Galr2

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_034384.3
• Gene: Galr2 / 14428
• MGIID: 1337018
• Length: 371
• Species: Mus musculus
• Alignment Length: 482
• Identity: 103/482 - (21%)
• Similarity: 164/482 - (34%)
• Gaps: 185/482 - (38%)

  Fly   178 VVPCYSA-ILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHF 241
            :||.:.| |.|...|||.||:..|::..:..:.||:|:|||.::|:...:.|:|.......|..:
Mouse    26 LVPLFFALIFLVGAVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDW 90

  Fly   242 IFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVC 306
            :||.||||.:.|....::..||:||.|:|.:||.||.:||.||..:|..:|...|.:||..:|:.
Mouse    91 VFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLF 155

  Fly   307 MTPIAAF---SQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRT 368
            ..|..::   |||     ..|..|...|.|..   .||.:|...:...:||:|.||.||   .||
Mouse   156 SGPYLSYYSQSQL-----ANLTVCHPAWSAPR---RRAMDLCTFVFSYLLPVLVLSLTY---ART 209

  Fly   369 LYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQY 433
            |:...|
Mouse   210 LHYLWR----------------------------------------------------------- 215

  Fly   434 YYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHR 498
                                                           |:....||:|
Mouse   216 -----------------------------------------------TVDPVAAGSG-------- 225

  Fly   499 MRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICW 563
                                                      |..:|::|.:|:.::.:.|.:||
Mouse   226 ------------------------------------------SQRAKRKVTRMIVIVAVLFCLCW 248

  Fly   564 TPLYVINTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVC 628
            .|.:.: .:.:..|........|.......|::|::||.|||.|..::..||:.|      .::|
Mouse   249 MPHHAL-ILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGF------RKIC 306

  Fly   629 ERLC--APCCFWRRRSKNETNLSVAGN 653
            ..|.  ||     ||:.....:...||
Mouse   307 AGLLRRAP-----RRASGRVCILAPGN 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	94/443 (21%)
		TM helix 1	178..202	CDD:410628	11/24 (46%)
		TM helix 2	211..233	CDD:410628	8/21 (38%)
		TM helix 3	249..271	CDD:410628	7/21 (33%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	9/22 (41%)
		TM helix 6	549..571	CDD:410628	5/21 (24%)
		TM helix 7	586..611	CDD:410628	9/24 (38%)
Galr2	NP_034384.3	7tmA_Gal2_Gal3_R	25..302	CDD:320225	94/443 (21%)
		TM helix 1	26..52	CDD:320225	11/25 (44%)
		TM helix 2	59..85	CDD:320225	9/25 (36%)
		TM helix 3	97..127	CDD:320225	12/29 (41%)
		TM helix 4	139..159	CDD:320225	5/19 (26%)
		TM helix 5	183..212	CDD:320225	13/31 (42%)
		TM helix 6	228..258	CDD:320225	7/30 (23%)
		TM helix 7	270..295	CDD:320225	9/24 (38%)