Protein Alignment CCKLR-17D1 and LOC1272152

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_311031.2
• Gene: LOC1272152 / 1272152
• VectorBaseID: AGAMI1_011227
• Length: 415
• Species: Anopheles gambiae
• Alignment Length: 531
• Identity: 127/531 - (23%)
• Similarity: 188/531 - (35%)
• Gaps: 190/531 - (35%)

  Fly   141 DMDLATTPSSSTLAPAVTVRTPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLTLVQNRR 205
            |.::.....:||:.|         ..:......|.:|:  .|:|||..::|||..|:..:....|
Mosquito    21 DDEILICDGASTIIP---------EGIASARFQVVVWL--AYTAILAASLVGNCSVLAIVASQPR 74

  Fly   206 MRTITNVFLLNLAISDILLGVFCMPVTLVGT-LLRHFIFGELLCKLIQFAQAASVAVSSWTLVAI 269
            |||:||:||.|||:.|:|:.:||:|.:.|.. :|:::.||..||:.:.:.||.||.||::||||:
Mosquito    75 MRTVTNLFLANLALGDLLMTLFCVPFSSVSLFVLQYWPFGAALCQTVNYFQAVSVLVSAYTLVAL 139

  Fly   270 SCERYYAICHPLRSRTWQTINH-ANKIIAIIWLGSLVCMTPIAAFSQLMPTS----RPGLRKCRE 329
            |.:||.||..|||||....... |..:|.::|:|:.....||...|.|:..|    ..|...|.|
Mosquito   140 SADRYRAIMWPLRSRRRPPRRPIALLLIGLVWVGAAATALPIPLHSALVQPSAWHAHCGQAVCTE 204

  Fly   330 QWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSA 394
            .||  ....:|||:|.|.||...|||..|.:||..|...::....|...
Mosquito   205 VWP--DATADRAYSLTLALAQFALPLGTLVYTYACIGWRVWARSTNRTG---------------- 251

  Fly   395 AVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHL 459
                                 :||...|..:|
Mosquito   252 ---------------------LVPPSSNSGRQ--------------------------------- 262

  Fly   460 YCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQP 524
                                                                             
Mosquito   263 ----------------------------------------------------------------- 262

  Fly   525 SLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVYEYVGYTSI 589
                    .||        :::|.|:|...:|..|.:||.|.     ..:||.|  .:...:..:
Mosquito   263 --------FRR--------ARRRTVRMTLAVVAAFVVCWLPF-----NALLLAP--LDDPSWAPL 304

  Fly   590 SFL----QLLAYSSSCCNPITYCFMNASFRRAF----VDTFKGMRVC--ERLCAPCCFWRRRSK- 643
            .:|    ..||.|..|.||:.||:|||.||..|    :.....:.||  .|....||..|.|:.
Mosquito   305 PYLWFACHWLAMSHCCLNPLIYCYMNAKFRAGFRALLLRPLMRVVVCRSRRTATTCCCLRHRAST 369

  Fly   644 --NETNLSVAG 652
              :...|.|.|
Mosquito   370 TVSSERLPVGG 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	111/450 (25%)
		TM helix 1	178..202	CDD:410628	8/23 (35%)
		TM helix 2	211..233	CDD:410628	11/21 (52%)
		TM helix 3	249..271	CDD:410628	10/21 (48%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	12/22 (55%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	9/28 (32%)
LOC1272152	XP_311031.2	None