Protein Alignment CCKLR-17D1 and LOC1271906

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_061514608.1
• Gene: LOC1271906 / 1271906
• VectorBaseID: AGAMI1_012393
• Length: 567
• Species: Anopheles gambiae
• Alignment Length: 621
• Identity: 157/621 - (25%)
• Similarity: 234/621 - (37%)
• Gaps: 234/621 - (37%)

  Fly   104 NEISAVGDGVTITGTPGDLL-----------NYSGLELDLGLDLDLNLDMDLATTP-SSST---- 152
            ||.:|.|.||..||..|:..           |.|......|.:|   .||.....| .|||
Mosquito    18 NESAAPGGGVYSTGPAGNGTGSGGFGALAGSNASSAGSAAGPEL---FDMYARNYPYVSSTEEQN 79

  Fly   153 ----LAPAVTVRT-PGNRSV-------------VRVSADVPIWVVPC---YSA------------ 184
                |:.::..:: .||||.             ..|..| ||.:..|   |||
Mosquito    80 YIEQLSDSLRNQSQAGNRSYGGAGGVGGAGGYDYGVGFD-PIPLAECSNAYSAGPYFQLTSYFLY 143

  Fly   185 --ILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGT-LLRHFIFGEL 246
              |.:.||:||.:|:..:..|.||||:||.|:.|||:.|:::.:||:|.|.:.. :|:::.||..
Mosquito   144 ITIFVTAVIGNSIVLFIVQSNPRMRTVTNFFITNLAVGDLMMTLFCVPFTFISLFVLQYWPFGLA 208

  Fly   247 LCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIA 311
            :|:|:.:.||.||.||::||||||.:||.||..|||.|..:|.:..  :|.|:|:.:|:...|||
Mosquito   209 MCRLVNYTQAVSVLVSAYTLVAISGDRYIAIMWPLRPRITKTCSKC--LIGIVWIIALITAVPIA 271

  Fly   312 AFSQL-MPTS---RPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVS 372
            .||.| .||.   :..:..|.|:||  |...:..|.:.|.....::||:.|.|||   ||...|.
Mosquito   272 IFSTLYFPTDWHVQCNVPICAEKWP--SPEQDDYYTIALLTTQFIVPLVVLIFTY---TRIAIVV 331

  Fly   373 MRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDY 437
                    :|...|
Mosquito   332 --------WGKRPP--------------------------------------------------- 337

  Fly   438 GHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQ 502
                                                                ||.
Mosquito   338 ----------------------------------------------------GEA---------- 340

  Fly   503 MQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLY 567
                                           ..|.:.:..:||::::||:..:|:.|.|||.|
Mosquito   341 -------------------------------ENSRDQRMAKSKRKMIKMMVTVVIVFTICWLP-- 372

  Fly   568 VINTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLC 632
             .|.:.::..|:.::.:.|...:| ..||.|.||.|||.||:|||.||..|:....|:...::||
Mosquito   373 -FNFLMLMKLPSSWDLLPYFWFAF-HWLAMSHSCYNPIIYCYMNARFRSGFILVLHGVPGLQQLC 435

  Fly   633 APCCFWRRRSKNETNLSVA---GNSIALANSVMSSH 665
              ||.      ..|..::|   |:|:|||.....||
Mosquito   436 --CCI------RHTPPAIARNVGSSVALAGIDEVSH 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	114/462 (25%)
		TM helix 1	178..202	CDD:410628	10/40 (25%)
		TM helix 2	211..233	CDD:410628	9/21 (43%)
		TM helix 3	249..271	CDD:410628	12/21 (57%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	7/22 (32%)
		TM helix 6	549..571	CDD:410628	8/21 (38%)
		TM helix 7	586..611	CDD:410628	12/24 (50%)
LOC1271906	XP_061514608.1	None