Protein Alignment CCKLR-17D1 and LOC1270512

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_061518622.1
• Gene: LOC1270512 / 1270512
• VectorBaseID: AGAMI1_007575
• Length: 805
• Species: Anopheles gambiae
• Alignment Length: 744
• Identity: 230/744 - (30%)
• Similarity: 324/744 - (43%)
• Gaps: 245/744 - (32%)

  Fly   114 TITGTPGDLLNYSGLELDLGLDLDLNLDMDLATT--------PSSSTLAPAVTVRTPGNRSVVRV 170
            ::.|..||.|..:.|.|.||..|..|:...:..|        .::..|.||....|.|:|
Mosquito    78 SMAGDYGDELYGTNLSLALGELLRDNISATVVGTHNLSGNGRSAAGNLPPATGTGTAGSR----- 137

  Fly   171 SADVPI---WVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVT 232
            ..|...   .::|.|:.|.|.:|||||||:|||.||:||||:|||:||||||||:||||||||.|
Mosquito   138 GGDGTFQNQLIIPLYAIIFLLSVVGNLLVILTLAQNKRMRTVTNVYLLNLAISDLLLGVFCMPFT 202

  Fly   233 LVGTLLRHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIA 297
            |.|.:||.|:||.::||||.:.||.||:|:.|||||||.|||:|||.||.||.|||..||.|:|.
Mosquito   203 LAGQVLRRFVFGSVMCKLIPYFQAVSVSVAVWTLVAISLERYFAICRPLSSRRWQTQFHAYKMIG 267

  Fly   298 IIWLGSLVCMTPIAAFSQLMPTSR-PGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFT 361
            ::|..|.:..:|:....:|:|..| .|..||||:||:.:  :||||.||.|:.||.||||.:.|.
Mosquito   268 LVWTVSFLANSPLGYVQRLLPVGRSTGQMKCREEWPSPA--WERAYVLFHDVGLLFLPLLTMGFA 330

  Fly   362 YLFITRTLYVSMRNE-------------------------------------------------- 376
            |..|...|:..:|:|
Mosquito   331 YSMIVSKLWRGLRHEIKHSSLYQQTSRQHGTGGQGSSVGGAPTGAAAGSVGTVSGEQHCSGDTGK 395

  Fly   377 -----------------------------RAMNFGSSGPEV---------TTSSSAAVAEAGSQR 403
                                         ..:||.|:...:         :.|||.....:||..
Mosquito   396 PPKPPGGKRHEPGFVLTSSLKKAPFKSSTAVVNFASNNNTINKSNFSGAGSGSSSNGAGSSGSSN 460

  Fly   404 RANGSHCQSLDT------------------IVPHQHNPHQQHHHHSQYYYDYGHCGSKR--RLIS 448
            .:||..|.....                  :...:|...:|||.|      .|.|.::|  |..:
Mosquito   461 GSNGGGCNGSGADQRTHYCGGAGCETRPGRLRGFRHFFAKQHHQH------VGLCRNQRYQRSST 519

  Fly   449 GGGPCEG--------------------RRHLYCMR-------------SASVKS----LRHQQIN 476
            ...| ||                    ..|.:|..             |..|||    .:|:.:.
Mosquito   520 AAAP-EGLPELAETKFDESASVGQQHPYHHCHCHHAHGYHHHHHRLPTSTIVKSTQQDAKHEIVL 583

  Fly   477 GGG----------------GTLSGTGA-----GNGECCSRVHRMRQQMQLQQQGYVSDNESRRKS 520
            |.|                |...|:.|     |.|:|                    |..:..
Mosquito   584 GTGEPGPGLEPAGDAVLLPGAPPGSAATAPETGQGDC--------------------DPSALN-- 626

  Fly   521 LSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPT-VYEYV 584
             ..|:.:.:...:|.:...||:|:||:|::||||:::|||:||.||:::||: .|..|| ||:||
Mosquito   627 -PDPAYQFSRHAIRSTYMDKSIEAKKKVIRMLFVIIVEFFVCWAPLHILNTV-YLYSPTFVYQYV 689

  Fly   585 GYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTF----KGMRVCERLCAPCC--------- 636
            ..:.|:.:||:||.|||||||||||||..||:||:..|    ..|.:|   |..||
Mosquito   690 NSSGIALVQLMAYISSCCNPITYCFMNRRFRQAFLGVFSCYRNRMPIC---CCFCCASSNGPMEG 751

  Fly   637 -------FWRRRSKNET-----NLSVAGN 653
                   :.|:.:.|::     |..::||
Mosquito   752 AESKAAAYLRQNTINQSGAERNNSDMSGN 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	199/608 (33%)
		TM helix 1	178..202	CDD:410628	14/23 (61%)
		TM helix 2	211..233	CDD:410628	18/21 (86%)
		TM helix 3	249..271	CDD:410628	14/21 (67%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	13/22 (59%)
		TM helix 6	549..571	CDD:410628	11/21 (52%)
		TM helix 7	586..611	CDD:410628	16/24 (67%)
LOC1270512	XP_061518622.1	None