Protein Alignment CCKLR-17D1 and LOC1269203

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_061518715.1
• Gene: LOC1269203 / 1269203
• VectorBaseID: AGAMI1_005583
• Length: 504
• Species: Anopheles gambiae
• Alignment Length: 494
• Identity: 93/494 - (18%)
• Similarity: 165/494 - (33%)
• Gaps: 205/494 - (41%)

  Fly   182 YSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISD--ILLGVFCMPVTLVGTLLRHFIFG 244
            |:.:.|..|:||.||:..:::...|:|:||:::|||||:|  .|:|:   |..:....::.:..|
Mosquito    61 YAVVCLVGVLGNTLVIYVVLRFSNMQTVTNMYILNLAIADECFLIGI---PFLIATMHMKRWTLG 122

  Fly   245 ELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTP 309
            ..:||....:.:.:...||..|..:|.:||.||||.:.|..::|...:..:..:.||.|.:.|.|
Mosquito   123 GAMCKAYMVSTSVTQFTSSIFLFIMSADRYIAICHHISSPKYRTPLVSRIVSLLAWLASALIMLP 187

  Fly   310 IAAFSQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALL--VLPLLALSFTYLFITRTLYVS 372
            |..::.:: ..:|....|:..|| ::..:...|...|...:|  |:||..:...|..:.|.|
Mosquito   188 IMIYADVI-EQKPNTYSCQILWP-ETHGHLPGYTFTLYSLILGFVIPLCFIMTFYCLVIRKL--- 247

  Fly   373 MRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDY 437
             ||        .||:.|
Mosquito   248 -RN--------VGPKTT------------------------------------------------ 255

  Fly   438 GHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQ 502
                         |...|:|                                     |.||
Mosquito   256 -------------GKSRGKR-------------------------------------RSHR---- 266

  Fly   503 MQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLY 567
                                                        :|.|::..::..:.:||.|.:
Mosquito   267 --------------------------------------------KVTKLVLTVITVYILCWLPYW 287

  Fly   568 V---------INTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFK 623
            :         ..|.:..|...::..||        .|.|.:|..|||.|.:::.:|:::|
Mosquito   288 ISQVALITSDFETCSTRLDLILFLLVG--------CLGYINSAINPILYAYLSENFKKSF----- 339

  Fly   624 GMRVCERLCAPCCFWRRRSKNETNLSVAGNSIALANSVM 662
             ::.|  .||        ::.|.|.     .:.|.||||
Mosquito   340 -LKAC--TCA--------ARAEVNA-----QLKLENSVM 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	82/448 (18%)
		TM helix 1	178..202	CDD:410628	7/19 (37%)
		TM helix 2	211..233	CDD:410628	10/23 (43%)
		TM helix 3	249..271	CDD:410628	4/21 (19%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	6/24 (25%)
		TM helix 6	549..571	CDD:410628	4/30 (13%)
		TM helix 7	586..611	CDD:410628	7/24 (29%)
LOC1269203	XP_061518715.1	None