Protein Alignment CCKLR-17D1 and qrfprb

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_017214090.3
• Gene: qrfprb / 101886159
• ZFINID: ZDB-GENE-131125-15
• Length: 433
• Species: Danio rerio
• Alignment Length: 545
• Identity: 120/545 - (22%)
• Similarity: 195/545 - (35%)
• Gaps: 216/545 - (39%)

  Fly   149 SSSTLAPAVTVRTPG---------NRS---------------VVRVSADVPIWVVPCYSAILLCA 189
            ||||...|.|..||.         |.|               :..:.|.|....|..|..|.:.|
Zfish     3 SSSTEMTATTKITPEVLQELLQYYNLSRQEFIDTYNIQPLVYIPELPAGVKSTFVVMYVIIFVLA 67

  Fly   190 VVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFA 254
            :|||.|||..:|:.|.:||.||:|:.:||:||:|:..||:|.||:..:...::.|.|:||.:.|.
Zfish    68 LVGNSLVVYVVVRKRAIRTATNIFICSLAVSDLLITFFCIPFTLLQNISSEWLGGVLVCKTVPFV 132

  Fly   255 QAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFSQLMPT 319
            |..::.....|:..|:.|||..|.:||:.:...|...|.:::.::|:.:::..:|: .|.|.:..
Zfish   133 QTTAIVTGILTMTCIAIERYQGIVYPLKMKRQYTPKRAYRMLGLVWIAAVMVGSPM-LFVQQLEV 196

  Fly   320 SRPGLRK-----CREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAM 379
            ....|..     |:|:|  .||...:.|..|:.:||.:|||.|:.|.|..|...|::..|
Zfish   197 KYDFLYDHHHVCCQERW--QSLLQRQLYTTFIMVALFLLPLAAMLFLYSRIGVELWIRKR----- 254

  Fly   380 NFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKR 444
                                                                             
Zfish   255 ----------------------------------------------------------------- 254

  Fly   445 RLISGGGPCEGRRHLYCMRSASVKS-LRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQ 508
                             :..|||.| :.|::|                  |::.|
Zfish   255 -----------------VGDASVLSTMNHREI------------------SKISR---------- 274

  Fly   509 GYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMT 573
                                               .|||.|||:..:||.|.:||.|.::::.:
Zfish   275 -----------------------------------KKKRAVKMMITIVLLFTVCWAPFHIVHML- 303

  Fly   574 MLLGPTVYEYVGYTS----------ISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVC 628
                   :||.....          |:.:|.:.:|:|..|||.|.|||.:|:::.:.|...
Zfish   304 -------FEYNDLEKKYNEVTVNMIIAVVQAIGFSNSFNNPIVYAFMNENFKKSCLSTLSS---- 357

  Fly   629 ERLCAPCCFWRR---RSKNETNLSV 650
                    :.||   :|....||||
Zfish   358 --------YLRRPVQQSVPRQNLSV 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	100/456 (22%)
		TM helix 1	178..202	CDD:410628	10/23 (43%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	5/21 (24%)
		TM helix 4	294..310	CDD:410628	1/15 (7%)
		TM helix 5	340..363	CDD:410628	9/22 (41%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	9/34 (26%)
qrfprb	XP_017214090.3	None