Protein Alignment CCKLR-17D1 and XB994602

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_002940541.3
• Gene: XB994602 / 100497124
• XenbaseID: XB-GENE-994603
• Length: 364
• Species: Xenopus tropicalis
• Alignment Length: 447
• Identity: 85/447 - (19%)
• Similarity: 152/447 - (34%)
• Gaps: 174/447 - (38%)

  Fly   179 VPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTL-LRHFI 242
            :|.|:.::..|.:||..::|.:...:::...||..:.|||::|:::.:||:|:|..... .|.::
 Frog    35 IPIYALLVTVACLGNCALILLIALTKKLHNTTNFLIGNLALADLVMCIFCVPLTASYAFENRGWL 99

  Fly   243 FGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCM 307
            |||.:|..:...|||:|.||..:|.||:.:||..:.:|:|.|.  .......|::::||.|:...
 Frog   100 FGEFMCHFVTLMQAATVCVSVLSLTAIAVDRYVVVVYPIRRRI--GCRSCIYIVSLVWLVSIGIS 162

  Fly   308 TPIAAFSQLMPTSRPG--LRKCREQWPADSLNYER---AYNLFLDLALLVLPLLALSFTYLFITR 367
            .|....:..:.....|  :..|.|.|    .|.|:   .|:..|.|...:|||.|::.:|
 Frog   163 MPTFFHTHYLDLKSAGHDMIICEEFW----RNQEKQRLLYSCSLLLLYYMLPLSAITISY----- 218

  Fly   368 TLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQ 432
                                      .|:|
 Frog   219 --------------------------CAIA----------------------------------- 222

  Fly   433 YYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVH 497
                                       |.:|..:|
 Frog   223 ---------------------------YHLRKRNV------------------------------ 230

  Fly   498 RMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFIC 562
                                             .|....|:.|..:.|::..:||.:.|:.|.||
 Frog   231 ---------------------------------PGATSHNQDKWSKKKQKTFRMLSISVMAFGIC 262

  Fly   563 WTPLYVINTMTMLLGPTVYEYVGYTSISFLQ----LLAYSSSCCNPITYCFMNASFR 615
            |.||.::|.:..:  ...:..:....|:.:|    |:|.||:|.||..|..::..||
 Frog   263 WLPLQILNLIRDI--DEEFAILDKNYINVIQVTCHLIAMSSACYNPFIYASLHDKFR 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	85/447 (19%)
		TM helix 1	178..202	CDD:410628	6/22 (27%)
		TM helix 2	211..233	CDD:410628	8/21 (38%)
		TM helix 3	249..271	CDD:410628	9/21 (43%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	7/25 (28%)
		TM helix 6	549..571	CDD:410628	9/21 (43%)
		TM helix 7	586..611	CDD:410628	10/28 (36%)
XB994602	XP_002940541.3	7tm_GPCRs	32..320	CDD:475119	85/447 (19%)
		TM helix 1	34..58	CDD:320516	6/22 (27%)
		TM helix 2	67..89	CDD:320516	8/21 (38%)
		TM helix 3	106..128	CDD:320516	9/21 (43%)
		TM helix 4	149..165	CDD:320516	4/15 (27%)
		TM helix 5	196..219	CDD:320516	8/53 (15%)
		TM helix 6	249..271	CDD:320516	9/21 (43%)
		TM helix 7	288..313	CDD:320516	9/24 (38%)