Protein Alignment CCKLR-17D1 and sstr2

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_002935929.1
• Gene: sstr2 / 100496382
• XenbaseID: XB-GENE-953419
• Length: 372
• Species: Xenopus tropicalis
• Alignment Length: 486
• Identity: 100/486 - (20%)
• Similarity: 183/486 - (37%)
• Gaps: 188/486 - (38%)

  Fly   140 LDMDLATTPSSSTLAPAVTVRTPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLTLVQNR 204
            ||:....||::::::.:.|.....:.:::..     |:.|.|  .:.||   ||.||:..:::..
 Frog    22 LDIFGRVTPTNASISNSTTYYDMTSNAILTF-----IYFVVC--IVGLC---GNTLVIYVILRYA 76

  Fly   205 RMRTITNVFLLNLAISD--ILLGV--FCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVSSWT 265
            :|:||||:::|||||:|  .:||:  ..|.|.||     |:.||:.:|:::......:...|.:.
 Frog    77 KMKTITNIYILNLAIADELFMLGLPFLAMQVALV-----HWPFGKAICRIVMTVDGINQFTSIFC 136

  Fly   266 LVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFSQLMPTSRPGLRKCREQ 330
            |..:|.:||.|:.||::|..|:....|..:.|.:|..||:.:.||..::.:.  |..|...|...
 Frog   137 LTVMSIDRYLAVVHPIKSAKWRRPRTAKMVNAAVWTVSLLVIMPIMTYAGVQ--SYHGRGSCTII 199

  Fly   331 WPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSAA 395
            ||.:|..:...:.::..:...::||..:...||||.
 Frog   200 WPGNSSAWYTGFIIYAFILGFLVPLSIICLCYLFII----------------------------- 235

  Fly   396 VAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLY 460
                                                                             
 Frog   236 ----------------------------------------------------------------- 235

  Fly   461 CMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPS 525
                ..|||             ||...|:                          |:||
 Frog   236 ----IKVKS-------------SGIRVGS--------------------------SKRK------ 251

  Fly   526 LRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVIN--TMTMLLGPTVYEYVGYTS 588
                             .|:|:|.:|:.::|..|..||.|.|:.|  ::::|:.||    .|..:
 Frog   252 -----------------RSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSLLIVPT----PGLKA 295

  Fly   589 I-SFLQLLAYSSSCCNPITYCFMNASFRRAF 618
            : .|:.:|:|::||.|||.|.|::.:|:::|
 Frog   296 MWDFVVVLSYANSCANPILYAFLSDNFKKSF 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	93/447 (21%)
		TM helix 1	178..202	CDD:410628	8/23 (35%)
		TM helix 2	211..233	CDD:410628	11/25 (44%)
		TM helix 3	249..271	CDD:410628	2/21 (10%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	2/22 (9%)
		TM helix 6	549..571	CDD:410628	8/23 (35%)
		TM helix 7	586..611	CDD:410628	10/25 (40%)
sstr2	XP_002935929.1	7tmA_SSTR2	48..326	CDD:320637	94/458 (21%)
		TM helix 1	49..75	CDD:320637	9/35 (26%)
		TM helix 2	82..108	CDD:320637	11/25 (44%)
		TM helix 3	119..149	CDD:320637	7/29 (24%)
		TM helix 4	161..183	CDD:320637	7/21 (33%)
		TM helix 5	208..237	CDD:320637	6/126 (5%)
		TM helix 6	252..282	CDD:320637	11/29 (38%)
		TM helix 7	294..319	CDD:320637	10/24 (42%)