Protein Alignment CCKLR-17D1 and npy2rl

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_017948295.1
• Gene: npy2rl / 100494553
• XenbaseID: XB-GENE-922375
• Length: 372
• Species: Xenopus tropicalis
• Alignment Length: 458
• Identity: 103/458 - (22%)
• Similarity: 170/458 - (37%)
• Gaps: 173/458 - (37%)

  Fly   174 VPIWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLL 238
            |.:.::..||.|:|..:|||.||:..:|:.:.|||:||.|:.||||:|:::..||:|.|||.||:
 Frog    42 VQVILIAAYSLIILLGLVGNSLVIYMIVKYKNMRTVTNFFIANLAIADLMVDSFCLPFTLVYTLM 106

  Fly   239 RHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGS 303
            ..:.||.:||.|..:|||.||.||:.||:.|:.:||:.|...|.||..:.::..  ||:|.|:.:
 Frog   107 DEWKFGSVLCHLFPYAQAMSVNVSTLTLIVIALDRYWCIVFHLNSRISKNLSFL--IISITWITA 169

  Fly   304 LVCMTPIAAFSQL----MPTSRPGLRKCREQWP-ADSLNYERAYNLFLDLALLVLPLLALSFTYL 363
            .:...|:|.|.:.    :|.....:..|.|.|. .||    ..|:|.:.:....|||..:.:.||
 Frog   170 AILAIPLAVFREFRYEDLPPFNLKIAVCAENWTNRDS----TIYSLSMLILQYALPLAVICYAYL 230

  Fly   364 FITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHH 428
                .::..::|
 Frog   231 ----RIWFKLKN----------------------------------------------------- 238

  Fly   429 HHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECC 493
                                         |:
 Frog   239 -----------------------------HI---------------------------------- 240

  Fly   494 SRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLE 558
                                         .|:.| :|:..||.|.|          |||.::|:.
 Frog   241 -----------------------------SPTTR-SESQQRRKNTT----------KMLVMMVVV 265

  Fly   559 FFICWTPLYVINTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFK 623
            |.:||.|.::.. :.:.|..||..:......:...::|..|:..||..|.:||.::|..|: ||.
 Frog   266 FAVCWLPFHIFQ-LAIDLEWTVAIHENKLLYTIFHVVAMCSTFVNPFLYGWMNKNYRHGFL-TFF 328

  Fly   624 GMR 626
            |.:
 Frog   329 GCK 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	98/445 (22%)
		TM helix 1	178..202	CDD:410628	9/23 (39%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	11/21 (52%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	8/21 (38%)
		TM helix 7	586..611	CDD:410628	5/24 (21%)
npy2rl	XP_017948295.1	7tm_GPCRs	44..324	CDD:475119	98/446 (22%)
		TM helix 1	46..70	CDD:410628	9/23 (39%)
		TM helix 2	79..101	CDD:410628	10/21 (48%)
		TM helix 3	117..139	CDD:410628	11/21 (52%)
		TM helix 4	160..176	CDD:410628	4/17 (24%)
		TM helix 5	207..230	CDD:410628	5/22 (23%)
		TM helix 6	256..278	CDD:410628	9/32 (28%)
		TM helix 7	292..317	CDD:410628	5/24 (21%)