Protein Alignment CCKLR-17D1 and brs3

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_002932668.2
• Gene: brs3 / 100488712
• XenbaseID: XB-GENE-960289
• Length: 402
• Species: Xenopus tropicalis
• Alignment Length: 453
• Identity: 94/453 - (20%)
• Similarity: 155/453 - (34%)
• Gaps: 181/453 - (39%)

  Fly   182 YSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGEL 246
            |:.|:...::||.:::....:.:.|:|:.|:|:.:||..|:||.:.|:||.....::..::||.:
 Frog    53 YAVIISVGLLGNTILIKVFFKVKSMQTVPNIFITSLAFGDLLLLLTCVPVDASRYMVDTWLFGRM 117

  Fly   247 LCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIA 311
            .||::.|.|..||.||.:||..:|.:||.||..||..:|...:.......|.:|:.|::...|.|
 Frog   118 GCKILSFIQLTSVGVSVFTLTVLSADRYRAIVKPLELQTSDAVLKTCGKAACVWIISMLLAAPEA 182

  Fly   312 AFSQLMPTSRP----GLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVS 372
            .||.|...|.|    ..:.| ..:|......:..::|...|...::||..:|..|:.|.:|||.|
 Frog   183 VFSDLYEFSSPDKNTSFKAC-APYPVSEKLMQETHSLMCFLVFYIVPLSIISAYYILIAKTLYKS 246

  Fly   373 MRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDY 437
            ..|                                              .|.::|.|
 Frog   247 TFN----------------------------------------------MPAEEHTH-------- 257

  Fly   438 GHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQ 502
                                                                             
 Frog   258 ----------------------------------------------------------------- 257

  Fly   503 MQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTP-- 565
                                               ..|.:||:|||.|.:.|||..|..||.|
 Frog   258 -----------------------------------ARKQIESRKRVAKTVLVLVALFAFCWLPNH 287

  Fly   566 -LYV---------INTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAF 618
             ||:         :|:..:.|..|:          |.::||:|:||.||....:::.|||:.|
 Frog   288 ILYLYRSFTYHSAVNSSMLHLSATI----------FARILAFSNSCVNPFALYWLSRSFRQHF 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	93/451 (21%)
		TM helix 1	178..202	CDD:410628	4/19 (21%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	9/21 (43%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	5/22 (23%)
		TM helix 6	549..571	CDD:410628	10/33 (30%)
		TM helix 7	586..611	CDD:410628	8/24 (33%)
brs3	XP_002932668.2	7tm_GPCRs	47..340	CDD:475119	93/451 (21%)
		TM helix 1	49..73	CDD:410628	4/19 (21%)
		TM helix 2	82..104	CDD:410628	10/21 (48%)
		TM helix 3	120..142	CDD:410628	9/21 (43%)
		TM helix 4	165..181	CDD:410628	3/15 (20%)
		TM helix 5	214..237	CDD:410628	5/22 (23%)
		TM helix 6	269..291	CDD:410628	9/21 (43%)
		TM helix 7	308..333	CDD:410628	10/34 (29%)