Protein Alignment CCKLR-17D1 and galr2

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_002940025.1
• Gene: galr2 / 100486593
• XenbaseID: XB-GENE-921716
• Length: 373
• Species: Xenopus tropicalis
• Alignment Length: 503
• Identity: 106/503 - (21%)
• Similarity: 174/503 - (34%)
• Gaps: 196/503 - (38%)

  Fly   157 VTVRTPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISD 221
            |:|:.....|....|..:|:    .||.|.|...|||.||:..|::|.::...||:|:|||.::|
 Frog     3 VSVQISSQDSCHPESVLIPV----LYSLIFLVGTVGNSLVLAVLLRNGKVNNTTNLFILNLGVAD 63

  Fly   222 ILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTW 286
            :...:||:|.......|..::||..:||.:.|....::..||:||..:|.:||.||.:|||||..
 Frog    64 LCFIIFCVPFQATIYTLDSWVFGPFMCKAVHFFIYLTMYASSFTLTTVSLDRYLAIRYPLRSREL 128

  Fly   287 QTINHANKIIAIIWLGSLVCMTPIAAFSQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALL 351
            :|..:|...|.:||..|||...|..::.|....|  .|..|...| .||  |.||.:|.......
 Frog   129 RTPKNALLAITLIWSLSLVFSGPYLSYYQEFQLS--NLTVCHPVW-QDS--YRRAMDLCTFAFSY 188

  Fly   352 VLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTI 416
            |:|:|.||.||....|.|:.::
 Frog   189 VIPVLILSLTYARTIRYLWTAV------------------------------------------- 210

  Fly   417 VPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGT 481
                                              .|.|..
 Frog   211 ----------------------------------DPIEDM------------------------- 216

  Fly   482 LSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKK 546
                                            :||:|                         :|:
 Frog   217 --------------------------------SESKR-------------------------AKR 224

  Fly   547 RVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVYEYVGYTSIS--------FLQLLAYSSSCCN 603
            ||.:|:.::.:.|.:||.|.:::         .:..:.||..::        ...|::|::||.|
 Frog   225 RVTRMIIIVAVLFCLCWLPHHLV---------ILCVWFGYFPLNNFTYALRILSHLVSYANSCVN 280

  Fly   604 PITYCFMNASFRRAFVDTFKGMRVCERLCAPCCFWRRRSKNETNLSVA 651
            |:.|..::..||:.|...|:           |...|:|:.|:.:.:.|
 Frog   281 PVVYALVSKHFRKGFRKIFR-----------CLLLRQRAANKVHTAPA 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	94/448 (21%)
		TM helix 1	178..202	CDD:410628	10/23 (43%)
		TM helix 2	211..233	CDD:410628	9/21 (43%)
		TM helix 3	249..271	CDD:410628	6/21 (29%)
		TM helix 4	294..310	CDD:410628	6/15 (40%)
		TM helix 5	340..363	CDD:410628	9/22 (41%)
		TM helix 6	549..571	CDD:410628	5/21 (24%)
		TM helix 7	586..611	CDD:410628	8/32 (25%)
galr2	XP_002940025.1	7tmA_Gal2_Gal3_R	18..295	CDD:320225	95/453 (21%)
		TM helix 1	19..45	CDD:320225	11/29 (38%)
		TM helix 2	52..78	CDD:320225	10/25 (40%)
		TM helix 3	90..120	CDD:320225	11/29 (38%)
		TM helix 4	132..152	CDD:320225	7/19 (37%)
		TM helix 5	176..205	CDD:320225	10/28 (36%)
		TM helix 6	221..251	CDD:320225	9/63 (14%)
		TM helix 7	263..288	CDD:320225	7/24 (29%)