Protein Alignment CCKLR-17D1 and LOC100333270

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_002666594.1
• Gene: LOC100333270 / 100333270
• -ID: -
• Length: 393
• Species: Danio rerio
• Alignment Length: 484
• Identity: 104/484 - (21%)
• Similarity: 168/484 - (34%)
• Gaps: 184/484 - (38%)

  Fly   174 VPIWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLL 238
            |.:|.| .::.:||.||.|||:|:..:|.::||||:||.||||||:||:.:......|..|....
Zfish    23 VALWSV-AFALVLLVAVTGNLIVIWIIVAHKRMRTVTNYFLLNLAVSDVCVAALNALVNFVYGAH 86

  Fly   239 RHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGS 303
            .|:.|....|:...|...|:|..|.:::.||:.:||.||.||::.|....:..|  :|..:|:.:
Zfish    87 GHWYFSSAYCRFQNFYPVAAVFASIYSMSAIALDRYMAIIHPMKPRLSAKVTKA--VIVCVWILA 149

  Fly   304 LVCMTPIAAFSQLMPTSRPGLRKCREQWPA---DSLNYERAYNLFLDLALLVLPLLALSFTYLFI 365
            .....|:..:|  :....|....|...||.   |:.    .|::.:.|.:.:|||..::.||..:
Zfish   150 AFLSFPLCFYS--VTEVLPHRTVCYVAWPRKDDDAF----IYHVVVALLVYLLPLALMAVTYSRV 208

  Fly   366 TRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHH 430
            ..||:           |...|
Zfish   209 GLTLW-----------GGDFP-------------------------------------------- 218

  Fly   431 SQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSR 495
                   ||                         :|...|.|
Zfish   219 -------GH-------------------------SSENLLDH----------------------- 228

  Fly   496 VHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFF 560
                                                          |::|::||||:.::|:.|.
Zfish   229 ----------------------------------------------LQAKRKVVKMMVIVVVTFA 247

  Fly   561 ICWTP---LYVINTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTF 622
            |||.|   .:::.:....|....:....|.|:.:|.:   |||..|||.||.:|:.||..|...|
Zfish   248 ICWLPYHVYFIVTSFNRALRRFKWIQQVYLSVLWLSM---SSSMYNPIIYCCLNSRFRAGFKRVF 309

  Fly   623 KGMRVCERLCAPCCFWRRRSKNETNLSVA 651
            :.          |.|.:..:.:|..|..|
Zfish   310 RW----------CPFIQMSNCDELELQTA 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	96/446 (22%)
		TM helix 1	178..202	CDD:410628	9/23 (39%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	6/21 (29%)
		TM helix 4	294..310	CDD:410628	2/15 (13%)
		TM helix 5	340..363	CDD:410628	6/22 (27%)
		TM helix 6	549..571	CDD:410628	9/24 (38%)
		TM helix 7	586..611	CDD:410628	11/24 (46%)
LOC100333270	XP_002666594.1	7tm_GPCRs	24..305	CDD:475119	96/448 (21%)
		TM helix 1	26..50	CDD:410628	10/24 (42%)
		TM helix 2	59..81	CDD:410628	10/21 (48%)
		TM helix 3	97..119	CDD:410628	6/21 (29%)
		TM helix 4	140..156	CDD:410628	3/17 (18%)
		TM helix 5	183..206	CDD:410628	6/26 (23%)
		TM helix 6	236..258	CDD:410628	9/21 (43%)
		TM helix 7	273..298	CDD:410628	11/27 (41%)