DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCKLR-17D1 and LOC100331465

DIOPT Version :9

Sequence 1:	NP_001097021.1	Gene:	CCKLR-17D1 / 32860	FlyBaseID:	FBgn0259231	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	XP_017213239.1	Gene:	LOC100331465 / 100331465	-ID:	-	Length:	442	Species:	Danio rerio

Alignment Length:	491	Identity:	152/491 - (30%)
Similarity:	229/491 - (46%)	Gaps:	134/491 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 YSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGEL 246
            |..|.|.:|.||||:::.|:.|:||||:||.|||:|||||:::.|.|||.||:..|:..||||..
Zfish    63 YCLIFLLSVFGNLLIIVVLMVNKRMRTVTNSFLLSLAISDLMMAVVCMPFTLIPNLMGDFIFGAA 127

  Fly   247 LCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIA 311
            :||::.:....||.:|:::||||:.|||.|||:||:||.|||.:||.|:||..|:.|.:.|||..
Zfish   128 MCKIVAYLMGISVCISTFSLVAIAIERYSAICNPLKSRAWQTRSHAYKVIASTWVVSFLIMTPYP 192

  Fly   312 AFSQLMPTSRPGL---RKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSM 373
            .||.|:..::...   ..||..|....:  |:|:.:.|...|..:|.:.:...|..|:|.||
Zfish   193 IFSTLVEFTKNNNITGHMCRHDWKNSEV--EKAWCILLLFVLFFIPGVVMIIAYGLISRELY--- 252

  Fly   374 RNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYG 438
               |.:.|     |:            .|::                                 |
Zfish   253 ---RGIQF-----EL------------EQKK---------------------------------G 264

  Fly   439 HCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQM 503
            .||.|..:                 ||:|              |..:..|:| |..:|.:....|
Zfish   265 QCGMKNGI-----------------SATV--------------LISSDDGDG-CYIQVSKRPNSM 297

  Fly   504 QLQQQGYVSDNESRRKSLSQPSLRITEAGLR-----RSNETKS-LESKKRVVKMLFVLVLEFFIC 562
            ::.                    .:|..|..     |||.::: |.:||||::||.|:|..||||
Zfish   298 EMS--------------------ALTPTGSAKVDRPRSNTSEAKLMAKKRVIRMLIVIVAMFFIC 342

  Fly   563 WTPLYVINTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRV 627
            |.|:|.:||.......:.:..:....|||:.||:|:|:|.|||.|||||..||:|.:.||.
Zfish   343 WMPVYSVNTWKAFDLASAHRALSGAPISFIHLLSYTSACVNPIIYCFMNKRFRKALLATFS---- 403

  Fly   628 CERLCAPCCFW--RRRS--KNETNLSVAGNSIALAN 659
                   ||.|  |:|.  :.:..::..|.|::..|
Zfish   404 -------CCCWPCRKRGFREGDDEVTATGASMSKFN 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_4	185..>308	CDD:304433	63/122 (52%)
CCKLR-17D1	NP_001097021.1	7tm_1	192..>380	CDD:278431	80/190 (42%)
LOC100331465	XP_017213239.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580892
Domainoid	1	1.000	229	1.000	Domainoid score	I2402
eggNOG	1	0.900	-	-		E33208_3BDYY
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7258
Inparanoid	1	1.050	261	1.000	Inparanoid score	I3097
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1042780at2759
OrthoFinder	1	1.000	-	-		FOG0001992
OrthoInspector	1	1.000	-	-		mtm6568
orthoMCL	1	0.900	-	-		OOG6_105354
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1306
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.660