Protein Alignment CCKLR-17D1 and qrfpra

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_021336543.1
• Gene: qrfpra / 100149491
• ZFINID: ZDB-GENE-090313-105
• Length: 422
• Species: Danio rerio
• Alignment Length: 508
• Identity: 101/508 - (19%)
• Similarity: 181/508 - (35%)
• Gaps: 191/508 - (37%)

  Fly   182 YSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGEL 246
            |:.|.|.|:|||.:||..:::.|.::|.||:|:.:||:||:|:..||:|.||:..:...:..|.|
Zfish    52 YTVIFLLALVGNSVVVYIVLRKRGIQTATNIFICSLAVSDLLISFFCIPFTLLQNISSEWFGGVL 116

  Fly   247 LCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIA 311
            :||.:.|.|..:|.....|:..|:.|||..|.|||:.:...|...|.:::.::|:.:::..:|:
Zfish   117 VCKTVPFVQTTAVVTGILTMTCIAVERYQGIVHPLKIKRQCTPQRAYRMLGVVWIAAMMVGSPM- 180

  Fly   312 AFSQLMPTSRPGLRK-----CREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYV 371
            .|.|.:......|..     |:|:|.:.:  :.:.|..|:.:.|.:|||.|:...|..|...|::
Zfish   181 LFVQQLEVKYDFLYDNHHVCCQERWRSSA--HRKRYATFILVFLFLLPLAAMLILYTRIGIELWI 243

  Fly   372 SMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYD 436
            ..:      .|.|          :|..|.:||..
Zfish   244 RKQ------VGDS----------SVLNAMNQREV------------------------------- 261

  Fly   437 YGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQ 501
                                                                             
Zfish   262 ----------------------------------------------------------------- 261

  Fly   502 QMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPL 566
                                                 :|....|:|.:||:..:|:.|.:||.|.
Zfish   262 -------------------------------------SKIARKKRRAIKMMVTIVVLFTVCWAPF 289

  Fly   567 YVINTMTMLLGPTVYEYVGYTS-----------ISFLQLLAYSSSCCNPITYCFMNASFRRAFVD 620
            :.::.:        :|| .|.:           |:..|.:.:|:|..|||.|.|||.:|::..:.
Zfish   290 HTVHIL--------FEY-SYLNKKYDDVTVNMIIAVAQAIGFSNSFNNPIIYAFMNENFQKNCMS 345

  Fly   621 TFKGMRVCERLCAPCCFWRRRSKNETNLSVAGNSIALANSVMSSHTILESPRL 673
            |   :.||          .|||.:..::. ..:.:....|......|...||:
Zfish   346 T---LSVC----------IRRSSHRVDVK-DKSKVLFCKSARQDEEISVMPRI 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	91/451 (20%)
		TM helix 1	178..202	CDD:410628	9/19 (47%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	6/21 (29%)
		TM helix 4	294..310	CDD:410628	1/15 (7%)
		TM helix 5	340..363	CDD:410628	7/22 (32%)
		TM helix 6	549..571	CDD:410628	7/21 (33%)
		TM helix 7	586..611	CDD:410628	10/35 (29%)
qrfpra	XP_021336543.1	7tmA_QRFPR	46..343	CDD:320333	91/451 (20%)
		TM helix 1	47..73	CDD:320333	9/20 (45%)
		TM helix 2	80..106	CDD:320333	13/25 (52%)
		TM helix 3	118..148	CDD:320333	10/29 (34%)
		TM helix 4	161..182	CDD:320333	3/21 (14%)
		TM helix 5	211..236	CDD:320333	8/24 (33%)
		TM helix 6	266..296	CDD:320333	9/37 (24%)
		TM helix 7	311..336	CDD:320333	9/24 (38%)