Protein Alignment CCKLR-17D1 and galr1

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001107355.1
• Gene: galr1 / 100135180
• XenbaseID: XB-GENE-5797254
• Length: 351
• Species: Xenopus tropicalis
• Alignment Length: 519
• Identity: 112/519 - (21%)
• Similarity: 180/519 - (34%)
• Gaps: 207/519 - (39%)

  Fly   121 DLLNYS-GLELDLGLDLDLNLDMDLATTPSSSTLAPAVTVRTPGNRSVVRVSADVPIWVVPCYSA 184
            |:.|.| |.|||                |:||.:..||       :.::.:..|..|.:| .:..
 Frog     6 DVRNDSEGFELD----------------PNSSEVPSAV-------KPLLGIGIDNVITLV-VFGM 46

  Fly   185 ILLCAVVGNLLVVLTLVQNR--RMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELL 247
            |....|:||.||:..|.:|:  :.|:.||:|:|||:|:|:...:||:|......:|..::.|..:
 Frog    47 IFALGVLGNSLVITVLARNKPGKPRSTTNIFILNLSIADLAYLLFCIPFQSTVYVLPTWVLGAFI 111

  Fly   248 CKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAA 312
            ||.|.:....|:.||.:||.|:|.:||.||.|..||...:...:|...:.:||:.|:...:|:|.
 Frog   112 CKFIHYFFTVSMLVSIFTLSAMSVDRYVAIVHSRRSSAIRVSRNALVGVIVIWILSIAMASPVAY 176

  Fly   313 FSQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNER 377
            ...|:..:....  |.|.||  :...:|.|.:...:...:||||.:||.|..:...|:..:||
 Frog   177 NQGLVYKNNQTF--CWESWP--NAQQKRIYVVCTFVFGYLLPLLLISFCYAKVLNHLHKKLRN-- 235

  Fly   378 AMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGS 442
                                                                             
 Frog   236 ----------------------------------------------------------------- 235

  Fly   443 KRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQ 507
                                                                             
 Frog   236 ----------------------------------------------------------------- 235

  Fly   508 QGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTM 572
                         :|:                ||..|||:..:.:.|:|:.|.|.|.|.:||:..
 Frog   236 -------------MSK----------------KSEASKKKTAQTVLVVVVVFGISWLPHHVIHLW 271

  Fly   573 TMLLGPTVYEYVGY--TSISFL-----QLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCE 629
            .        ||..:  |..||:     ..||||:|..|||.|.|::.:||:|:...||....|:
 Frog   272 V--------EYGSFPLTQASFVFRIVAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCQIGCD 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	94/449 (21%)
		TM helix 1	178..202	CDD:410628	8/23 (35%)
		TM helix 2	211..233	CDD:410628	10/21 (48%)
		TM helix 3	249..271	CDD:410628	8/21 (38%)
		TM helix 4	294..310	CDD:410628	3/15 (20%)
		TM helix 5	340..363	CDD:410628	8/22 (36%)
		TM helix 6	549..571	CDD:410628	8/21 (38%)
		TM helix 7	586..611	CDD:410628	13/31 (42%)
galr1	NP_001107355.1	7tmA_Gal1_R	38..316	CDD:320226	95/451 (21%)
		TM helix 1	39..65	CDD:320226	9/26 (35%)
		TM helix 2	74..100	CDD:320226	11/25 (44%)
		TM helix 3	112..142	CDD:320226	13/29 (45%)
		TM helix 4	154..174	CDD:320226	4/19 (21%)
		TM helix 5	199..228	CDD:320226	9/28 (32%)
		TM helix 6	242..272	CDD:320226	11/29 (38%)
		TM helix 7	284..309	CDD:320226	11/24 (46%)