Protein Alignment CCKLR-17D1 and tacr1a

DIOPT Version :10

• Sequence 1: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001257407.1
• Gene: tacr1a / 100003539
• ZFINID: ZDB-GENE-060526-185
• Length: 426
• Species: Danio rerio
• Alignment Length: 475
• Identity: 106/475 - (22%)
• Similarity: 171/475 - (36%)
• Gaps: 194/475 - (40%)

  Fly   174 VPIWVVPCYSAILLCAVVGNLLVVLTLVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLL 238
            :.:|.| .||.|::.:||||:.|:..::.::||||:||.||:|||.::..:..|...:..|.::.
Zfish    38 IVLWAV-AYSTIVVVSVVGNITVIWIILAHKRMRTVTNYFLVNLAFAEASMSAFNTVINFVYSVH 101

  Fly   239 RHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGS 303
            ..:.||...|:...|...|:|..|.:::.||:.:||.||.|||:.|  .:......:|.:||:.:
Zfish   102 NEWYFGLYYCRFHNFFPIAAVFASIYSMTAIALDRYMAIIHPLQQR--MSATQTKVVIGVIWILA 164

  Fly   304 LVCMTPIAAFS---QLMPTSRPGLRKCREQWPADS-LNYERAYNLFLDLALLV--LPLLALSFTY 362
            |:...|...:|   ||     ||...|...||..: |:::..|  |:.:|:|:  ||||.:...|
Zfish   165 LLLAFPQYYYSDTDQL-----PGRVVCYIDWPEYTLLDFKTMY--FVCVAVLIYFLPLLVMGCAY 222

  Fly   363 LFITRTLYVSMRNERAMNFGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQH 427
            |.:..||:.|              |:...||.
Zfish   223 LVVGLTLWAS--------------EIPGDSSD--------------------------------- 240

  Fly   428 HHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGEC 492
                                                       |:|:
Zfish   241 -------------------------------------------RYQE------------------ 244

  Fly   493 CSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVL 557
                                                            .|.:|::||||:.|:|.
Zfish   245 ------------------------------------------------QLTAKRKVVKMMIVVVC 261

  Fly   558 EFFICWTPLYVINTMTMLLGPTVYEYVGYTSISFLQ-------LLAYSSSCCNPITYCFMNASFR 615
            .|.:||.|.:|...:.... |.::|:      :|:|       .||.||:..|||.||.:|..||
Zfish   262 TFAVCWLPYHVYFLIHQFY-PHLFEH------TFIQQVYLTIMWLAMSSTMYNPIIYCCLNDRFR 319

  Fly   616 RAFVDTFKGMRVCERLCAPC 635
            ..|...|:        |.||
Zfish   320 AGFKQAFR--------CCPC 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKLR-17D1	NP_001097021.1	7tm_GPCRs	177..618	CDD:475119	101/453 (22%)
		TM helix 1	178..202	CDD:410628	9/23 (39%)
		TM helix 2	211..233	CDD:410628	7/21 (33%)
		TM helix 3	249..271	CDD:410628	6/21 (29%)
		TM helix 4	294..310	CDD:410628	4/15 (27%)
		TM helix 5	340..363	CDD:410628	8/24 (33%)
		TM helix 6	549..571	CDD:410628	10/21 (48%)
		TM helix 7	586..611	CDD:410628	11/31 (35%)
tacr1a	NP_001257407.1	7tmA_NK1R	39..322	CDD:320668	101/455 (22%)
		TM helix 1	40..66	CDD:320668	10/26 (38%)
		TM helix 2	73..99	CDD:320668	9/25 (36%)
		TM helix 3	111..141	CDD:320668	10/29 (34%)
		TM helix 4	152..173	CDD:320668	5/20 (25%)
		TM helix 5	199..228	CDD:320668	10/30 (33%)
		TM helix 6	247..277	CDD:320668	12/29 (41%)
		TM helix 7	290..315	CDD:320668	10/24 (42%)