Protein Alignment Cyp308a1 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_573320.1
• Gene: Cyp308a1 / 32859
• FlyBaseID: FBgn0030949
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 557
• Identity: 128/557 - (22%)
• Similarity: 241/557 - (43%)
• Gaps: 133/557 - (23%)

  Fly     2 LPLVLFILLAATLLFWKWQGNH----WRRLGLEAPFGWPLVGNMLDFALGR--------RSYGEI 54
            |.:..::||..:|:|:...|.:    :::||:..|...||.||::::..|.        :.||:|
Mouse     7 LSIQTWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGNIINYLDGMWKFDDDCYKKYGKI 71

  Fly    55 YQEIYTRNPGLKYVGFYRLFNEPAILVRDQELLRQILVGRNFADCADNAVYVDHQRDVLASHNPF 119
            :             |||. ..:|.:.:.|.|:::.:||...::              |..:..||
Mouse    72 W-------------GFYE-GPQPILAIMDPEIIKIVLVKECYS--------------VFTNRRPF 108

  Fly   120 -----------IANGDRWRVLRADLVPLFTPSRVRQTLPHVARACQLL-----RDQVPLGRFEAK 168
                       |:..:.|:.||..|.|.||.|::::..|.:.:...:|     |::........|
Mouse   109 GPVGFLKKSITISEDEEWKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMK 173

  Fly   169 DLATRYTLQVVASAIFGLDAHCLGIHMRVAHEPSRWLEWLAPL-----FQPSVWSLLETMSLLHT 228
            |:...|::.|:.....|::...|.      :....:::.:..:     |.|.:.|::....|  |
Mouse   174 DIFGAYSMDVITGTSCGVNIDSLN------NPQDPFVQKIKKILKFKFFDPFLLSVVLFPFL--T 230

  Fly   229 PRLGRLIGHRYVPLPLQHWFRELVEARSGGDNL----------LQWLAESKRGLGKE-------- 275
            | :..::.....|....::|::.|: :...|.|          ||.:..::...|:|
Mouse   231 P-IYEMLNLSIFPRQSMNFFKKFVK-KMKKDRLDYNQKNRVDFLQLMMNTQNSKGQESLKALSDL 293

  Fly   276 ELAGHATTLLLEGYETSAMLLAFALYELALNEDAQRRLHIELDEVAQRHAGNLIDPVALGELRYS 340
            |:|......:..||:.::..::|.:||||.:.|.|::|..|:|......|....|  ||.::.|.
Mouse   294 EMAAQTLIFIFGGYDGTSTSISFIMYELATHPDVQKKLQDEIDRALPNKAPVTYD--ALMDMEYL 356

  Fly   341 EAALLEALRLHPAMQALQKRCTKTFTLPDQKSGASSELKVH-----LGTVLVLPVQAIHLDPALY 400
            :..:.|:|||:|.:..:.:...|             ::::|     .||::::|:..:|.||..:
Mouse   357 DMVVNESLRLYPVVSRIDRFSKK-------------DVEIHGVFIPKGTIVMIPIYPLHRDPEYW 408

  Fly   401 PAPNQFRPERFLNQ------PPMGCRFLGFGAGPRMCPGMRLGLLQTKAALTTLLQDHCVQLADE 459
            |.|..|.||||..:      |.:   ::.||.|||.|.|||..|:..|.|:|.:||:..||..:|
Mouse   409 PEPEDFCPERFSKENKGNIDPYI---YMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEE 470

  Fly   460 DQCRVEVS---------PLTFLTASRNGIWLSFKRRT 487
            .|..|::|         |:.....||:      |.||
Mouse   471 TQIPVKISRQPIFRPEKPIILKFVSRD------KPRT 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp308a1	NP_573320.1	CYP6-like	63..480	CDD:410679	108/475 (23%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	109/480 (23%)