Protein Alignment Cyp308a1 and Cyp3a25

DIOPT Version :9

• Sequence 1: NP_573320.1
• Gene: Cyp308a1 / 32859
• FlyBaseID: FBgn0030949
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 538
• Identity: 123/538 - (22%)
• Similarity: 238/538 - (44%)
• Gaps: 95/538 - (17%)

  Fly     2 LPLVLFILLAATLLFWKWQGNH----WRRLGLEAPFGWPLVGNMLDFALGR--------RSYGEI 54
            |.:..::||..:|:.:...|.:    :::||:..|...||:|.:.::..|.        :.||:|
Mouse     7 LSIETWVLLVTSLVLFYIYGTYSHGLFKKLGIPGPKPLPLLGTIFNYYDGMWKFDEDCYKKYGKI 71

  Fly    55 YQEIYTRNPGLKYVGFYRLFNEPAILVRDQELLRQILVGRNFADCADNAVY--VDHQRDVLASHN 117
            :             |||. ..:|.:.:.|.|:::.:||...::...:...:  |...:..:.
Mouse    72 W-------------GFYE-GPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAIT--- 119

  Fly   118 PFIANGDRWRVLRADLVPLFTPSRVRQTLPHVARACQLL-----RDQVPLGRFEAKDLATRYTLQ 177
              |:..:.|:.||..|.|.||..::::..|.:.:...:|     |::........||:...|::.
Mouse   120 --ISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSMD 182

  Fly   178 VVASAIFGLDAHCLGIHM-RVAHEPSRWLEWLAPLFQPSVWSLLETMSLLHTPRLGRLIGHRYVP 241
            |:....||::...|.... ....:..:.|::  .:|.|.:.|::....|  || :..::.....|
Mouse   183 VITGTSFGVNVDSLNNPQDPFVQKAKKILKF--KIFDPFLLSIILFPFL--TP-IYEMLNFSIFP 242

  Fly   242 LPLQHWFRELVE------ARSGGDNLLQWL-----------AESKRGLGKEELAGHATTLLLEGY 289
            ....::|::.|:      ..|...|.:.:|           .||::.|...|:|..|...:..||
Mouse   243 RDSMNFFKKFVKRMKKERLASNQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVIFIFGGY 307

  Fly   290 ETSAMLLAFALYELALNEDAQRRLHIELDEVAQRHAGNLIDPVALGELRYSEAALLEALRLHPAM 354
            :.::..::..:||||.:.|.|::|..|:|......|....|  ||.::.|.:..:.|:|||:|..
Mouse   308 DATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYD--ALMDMEYLDMVVNESLRLYPIA 370

  Fly   355 QALQKRCTKTFTLPDQKSGASSELKVHLGTVLVLPVQAIHLDPALYPAPNQFRPERFLNQ----- 414
            ..|::...|...:        :.:.:..|||:::|:..:|.:|..:|.|.:|.||||..:
Mouse   371 IRLERVSKKDVEI--------NGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSKENKGNI 427

  Fly   415 -PPMGCRFLGFGAGPRMCPGMRLGLLQTKAALTTLLQDHCVQLADEDQCRVEVS---------PL 469
             |.:   ::.||.|||.|.|||..|:..|.|:..:||:..||..:|.|..:::|         |:
Mouse   428 DPYI---YMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPLKISREPIFQPEKPI 489

  Fly   470 TFLTASRNGIWLSFKRRT 487
            .....||:      |.||
Mouse   490 ILKVVSRD------KPRT 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp308a1	NP_573320.1	p450	32..481	CDD:299894	113/496 (23%)
Cyp3a25	NP_062766.2	p450	39..493	CDD:278495	111/490 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820