DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp308a1 and Cyp309a1

DIOPT Version :9

Sequence 1:	NP_573320.1	Gene:	Cyp308a1 / 32859	FlyBaseID:	FBgn0030949	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001259943.1	Gene:	Cyp309a1 / 33438	FlyBaseID:	FBgn0031432	Length:	506	Species:	Drosophila melanogaster

Alignment Length:	487	Identity:	132/487 - (27%)
Similarity:	216/487 - (44%)	Gaps:	57/487 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLFILLAATLLFWKWQGNHWRRLGLEAPFGWPLVGNMLDFALGR-RSYGEIYQEIYTRNPGLKYV 68
            ::.:..|....:..|...:|.:.|:.......::|:.....:.: ||.....|::|.     ||.
  Fly    11 IVHVAFAVVYFYLTWYHKYWDKRGVVTAEPLTILGSYPGILINKSRSLILDVQDVYN-----KYK 70

  Fly    69 GFYR-----LFNEPAILVRDQELLRQILVGR--NFADCADNAVYVDHQRDVLASHNPFIANGDRW 126
            ..||     :..:|.:||.|..|..:|||.:  :|.|...::....:..|...:.:||.:.||:|
  Fly    71 DKYRTVGTFITRQPQLLVLDPALAHEILVDKFSHFRDTITSSFVGHNPDDKYVAGSPFFSAGDKW 135

  Fly   127 RVLRADLVPLFTPSRV-----------RQTLPHVARACQLLRDQVPLGRFEAKDLATRYTLQVVA 180
            :.||::.|...||||:           |:.:.::.||   .|:|..:  .|.:|||.|:|...:|
  Fly   136 KRLRSENVGGLTPSRLKMAYSIWEQSGRKLVEYIERA---RREQGDI--IETRDLAYRFTANAMA 195

  Fly   181 SAIFGLDAHCL-GIHMRVAHEPSRWLEWLAPLFQPSVWSLLETMSLLHTPRLGRLIGHRYVPLPL 244
            ..|:|:||..| |....:........:|.|..|.    |::.....|....:.:|...|:.....
  Fly   196 DFIWGIDAGSLSGKVGEIGDFQKTSTDWSAHAFS----SMIRFNKTLVAIFVRKLFSMRFFTKAT 256

  Fly   245 QHWF----RELVEARSGG------DNLLQWLAESKRGLGKEELAGHATTLLLEGYETSAMLLAFA 299
            ..:|    ::.|..|.||      |.|...:...:||....:..|||.|:.|:|:|||..:|...
  Fly   257 DEFFLRLTQDAVNLRQGGSGEGRTDYLSHLIQLQQRGNSIHDSVGHALTVHLDGFETSGAVLYHM 321

  Fly   300 LYELALNEDAQRRLHIELDEVAQRHAGNLIDPVALGELRYSEAALLEALRLHPAMQALQKRCTKT 364
            ||.|:.:.:.|.:|..|:.|..........|.:  ..|.|.:....|:|||...:....:.|||
  Fly   322 LYSLSEHHEEQEKLRSEILEALASEGQISYDQI--NNLPYLDQCFNESLRLTTPIGFFMRICTK- 383

  Fly   365 FTLPDQ-KSGASSELKVHLGTVLVLPVQAIHLDPALYPAPNQFRPERFLN-----QPPMGCRFLG 423
               |.| ..|....|.:..|..:::|....|.|..:||..::|||:||.|     ....|| ||.
  Fly   384 ---PTQINLGDDKTLDLEPGVTVMVPAYQYHHDNDIYPEASEFRPDRFENGAASVLTKRGC-FLP 444

  Fly   424 FGAGPRMCPGMRLGLLQTKAALTTLLQDHCVQ 455
            ||.|||:|.|||:|.|..|.|:..:|.::.|:
  Fly   445 FGDGPRICLGMRVGQLSVKTAIVHILSNYQVE 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp308a1	NP_573320.1	p450	32..481	CDD:299894	128/460 (28%)
Cyp309a1	NP_001259943.1	p450	49..481	CDD:299894	127/449 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472982
Domainoid	1	1.000	88	1.000	Domainoid score	I2119
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I1773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	6.000