Protein Alignment Cyp308a1 and CYP3A7-CYP3A51P

DIOPT Version :9

• Sequence 1: NP_573320.1
• Gene: Cyp308a1 / 32859
• FlyBaseID: FBgn0030949
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001243426.2
• Gene: CYP3A7-CYP3A51P / 100861540
• HGNCID: 51504
• Length: 535
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 132/538 - (24%)
• Similarity: 230/538 - (42%)
• Gaps: 109/538 - (20%)

  Fly     2 LPLVLFILLAATLLFWKWQGNH----WRRLGLEAPFGWPLVGNMLDFALGRRSYGEIYQEIYTRN 62
            |.:..::|||.:|:.....|..    :::||:..|...|.:||.|.|   |:.|.....|.|.
Human     7 LAVETWLLLAVSLILLYLYGTRTHGLFKKLGIPGPTPLPFLGNALSF---RKGYWTFDMECYK-- 66

  Fly    63 PGLKYVGFYRLFN--EPAILVRDQELLRQILVGRNFADCADNAVYVDHQRDVLASHNPF------ 119
               ||...:.:::  :|.:.:.|.::::.:||...::              |..:..||
Human    67 ---KYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYS--------------VFTNRRPFGPVGFM 114

  Fly   120 -----IANGDRWRVLRADLVPLFTPSRVRQTLPHVAR----ACQLLRDQVPLGR-FEAKDLATRY 174
                 ||..:.|:.:|:.|.|.||..::::.:|.:|:    ..:.||.:...|: ...|.:...|
Human   115 KNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAY 179

  Fly   175 TLQVVASAIFGLDAHCLGIHMRVAHEPSRWLEWLAPLFQPSVWS---------LLETMSLLHTPR 230
            ::.|:.|..||:....|........|.::.|....|| .|.|.|         :||.:::...||
Human   180 SMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPL-DPFVLSIKVFPFLTPILEALNITVFPR 243

  Fly   231 L--------------GRL---IGHRYVPLPLQHWFRELVEARSGGDNLLQWLAESKRGLGKEELA 278
            .              |||   ..||...|.|      ::::::..|      :|:.:.|...||.
Human   244 KVISFLTKSVKQIKEGRLKETQKHRVDFLQL------MIDSQNSKD------SETHKALSDLELM 296

  Fly   279 GHATTLLLEGYETSAMLLAFALYELALNEDAQRRLHIELDEVAQRHAGNLIDPVALGELRYSEAA 343
            ..:...:..||||::.:|:|.:||||.:.|.|:::..|:|.|....|....|.|.  :|.|.:..
Human   297 AQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL--QLEYLDMV 359

  Fly   344 LLEALRLHPAMQALQKRCTKTFTLPDQKSGASSELKVHLGTVLVLPVQAIHLDPALYPAPNQFRP 408
            :.|.|||.|....|::.|.|...:        :.:.:..|.|:::|...:|.||..:..|.:|.|
Human   360 VNETLRLFPVAMRLERVCKKDVEI--------NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLP 416

  Fly   409 ERFL-----NQPPMGCRFLGFGAGPRMCPGMRLGLLQTKAALTTLLQDHCVQLADEDQCRVEV-- 466
            |||.     |..|.  .:..||:|||.|.|||..|:..|.||..:||:...:...|.|..:::
Human   417 ERFSKKNKDNIDPY--IYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRF 479

  Fly   467 -------SPLTFLTASRN 477
                   .|:.....||:
Human   480 GGLLLTEKPIVLKAESRD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp308a1	NP_573320.1	p450	32..481	CDD:299894	124/504 (25%)
CYP3A7-CYP3A51P	NP_001243426.2	p450	39..492	CDD:278495	122/499 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820